Modelling Spontaneous Ca2+ Oscillations Using a Digital Astrocyte System Based on Single-Electron Transistors
This work presents an improved version of a digital nanoelectronic astrocyte. This module simulates the spontaneous Ca2+ oscillations in the cytosol. Ca2+ oscillations are often initiated by stimuli from neighboring neurons, but they can also be triggered by small calcium ions flow from the external...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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IFSA Publishing, S.L.
2021-01-01
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| Series: | Sensors & Transducers |
| Subjects: | |
| Online Access: | https://sensorsportal.com/HTML/DIGEST/january_2021/Vol_248/P_3197.pdf |
| Summary: | This work presents an improved version of a digital nanoelectronic astrocyte. This module simulates the spontaneous Ca2+ oscillations in the cytosol. Ca2+ oscillations are often initiated by stimuli from neighboring neurons, but they can also be triggered by small calcium ions flow from the external environment into the astrocyte’s cytosol. The hardware presented is a single-electron transistor-based model with a reduced footprint in relation to other digital astrocytes that implement the same model, and it generates the spontaneous oscillations without great loss of precision. |
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| ISSN: | 2306-8515 1726-5479 |