Plasmodium-specific atypical memory B cells are short-lived activated B cells

Plasmodium-specific atypical memory B cells are short-lived activated B cells

A subset of atypical memory B cells accumulates in malaria and several infections, autoimmune disorders and aging in both humans and mice. It has been suggested these cells are exhausted long-lived memory B cells, and their accumulation may contribute to poor acquisition of long-lasting immunity to...

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Bibliographic Details
Main Authors: Damián Pérez-Mazliah, Peter J Gardner, Edina Schweighoffer, Sarah McLaughlin, Caroline Hosking, Irene Tumwine, Randall S Davis, Alexandre J Potocnik, Victor LJ Tybulewicz, Jean Langhorne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
atypical memory B cells
age-associated B cells
Plasmodium
malaria
mosquito
FCRL5
Online Access:https://elifesciences.org/articles/39800

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