Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity

Abstract Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF‐α display pro‐inflammatory actions on endothelial cells and atherosclerotic plaques....

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Bibliographic Details
Main Authors: Silvia Oggero, Monica deGaetano, Simone Marcone, Stephen Fitzsimons, Andreia L. Pinto, Dinara Ikramova, Mary Barry, David Burke, Trinidad Montero‐Melendez, Dianne Cooper, Thomas Burgoyne, Orina Belton, Lucy V. Norling, Eoin P. Brennan, Catherine Godson, Mauro Perretti
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
monocyte/platelet aggregates
proteomics
vascular inflammation
Online Access:https://doi.org/10.1002/jev2.12084

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