Optimized Silica-Binding Peptide-Mediated Delivery of Bactericidal Lysin Efficiently Prevents <i>Staphylococcus aureus</i> from Adhering to Device Surfaces

Optimized Silica-Binding Peptide-Mediated Delivery of Bactericidal Lysin Efficiently Prevents <i>Staphylococcus aureus</i> from Adhering to Device Surfaces

Staphylococcal-associated device-related infections (DRIs) represent a significant clinical challenge causing major medical and economic sequelae. Bacterial colonization, proliferation, and biofilm formation after adherence to surfaces of the indwelling device are probably the primary cause of DRIs....

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Bibliographic Details
Main Authors: Wan Yang, Vijay Singh Gondil, Dehua Luo, Jin He, Hongping Wei, Hang Yang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
lysin
<i>Staphylococcus aureus</i>
silica-binding peptide
antimicrobial agents immobilization
surface functionalization
antimicrobial agents
Online Access:https://www.mdpi.com/1422-0067/22/22/12544

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