Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma

<p>Abstract</p> <p>Background</p> <p>The Juniper Asthma Specific Quality of Life Questionnaire (AQLQ(S)) is a questionnaire that allows measurement of disease specific quality of life. We wanted to examine correlations between the (AQLQ(S)) general and different subscal...

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Main Authors: Ghezzo Heberto, L'Archeveque Jocelyne, Lavoie Kim L, Miedinger David, Malo Jean-Luc
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Health and Quality of Life Outcomes
Subjects:
Online Access:http://www.hqlo.com/content/9/1/76
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author Ghezzo Heberto
L'Archeveque Jocelyne
Lavoie Kim L
Miedinger David
Malo Jean-Luc
author_facet Ghezzo Heberto
L'Archeveque Jocelyne
Lavoie Kim L
Miedinger David
Malo Jean-Luc
author_sort Ghezzo Heberto
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>The Juniper Asthma Specific Quality of Life Questionnaire (AQLQ(S)) is a questionnaire that allows measurement of disease specific quality of life. We wanted to examine correlations between the (AQLQ(S)) general and different subscale scores and both psychiatric morbidity and levels of psychological distress in individuals with occupational asthma (OA) and to determine if results in the emotional function subscale allow identification of individuals with clinically significant psychological distress or current psychiatric disorders.</p> <p>Methods</p> <p>This was a cross-sectional study of individuals with OA who were assessed during a re-evaluation for permanent disability, after they were no longer exposed to the sensitizing agent. Patients underwent a general sociodemographic and medical history evaluation, a brief psychiatric interview (Primary Care Evaluation of Mental Disorders, PRIME-MD) and completed a battery of questionnaires including the AQLQ(S), the St-Georges Respiratory Questionnaire (SGRQ), and the Psychiatric Symptom Index (PSI).</p> <p>Results</p> <p>There was good internal consistency (Cronbach alpha = 0.936 for the AQLQ(S) total score) and construct validity for the AQLQ(S) (Spearman rho = -0.693 for the SGRQ symptom score and rho = -0.650 for the asthma severity score). There were medium to large correlations between the total score of the AQLQ(S) and the SGRQ symptom score (r = -.693), and PSI total (r = -.619) and subscale scores (including depression, r = -.419; anxiety, r = -.664; anger, r = -.367; cognitive disturbances, r = -.419). A cut-off of 5.1 on the AQLQ(S) emotional function subscale (where 0 = high impairment and 7 = no impairment) had the best discriminative value to distinguish individuals with or without clinically significant psychiatric distress according to the PSI, and a cut-off of 4.7 best distinguished individuals with or without a current psychiatric disorder according to the PRIME-MD.</p> <p>Conclusions</p> <p>Impaired quality of life is associated with psychological distress and psychiatric disorders in individuals with OA. Findings suggest that the AQLQ(S) questionnaire may be used to identify patients with potentially clinically significant levels of psychological distress.</p>
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spelling doaj.art-e2e6a87f398049a7bdbb76dc7691de7f2022-12-22T03:25:53ZengBMCHealth and Quality of Life Outcomes1477-75252011-09-01917610.1186/1477-7525-9-76Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthmaGhezzo HebertoL'Archeveque JocelyneLavoie Kim LMiedinger DavidMalo Jean-Luc<p>Abstract</p> <p>Background</p> <p>The Juniper Asthma Specific Quality of Life Questionnaire (AQLQ(S)) is a questionnaire that allows measurement of disease specific quality of life. We wanted to examine correlations between the (AQLQ(S)) general and different subscale scores and both psychiatric morbidity and levels of psychological distress in individuals with occupational asthma (OA) and to determine if results in the emotional function subscale allow identification of individuals with clinically significant psychological distress or current psychiatric disorders.</p> <p>Methods</p> <p>This was a cross-sectional study of individuals with OA who were assessed during a re-evaluation for permanent disability, after they were no longer exposed to the sensitizing agent. Patients underwent a general sociodemographic and medical history evaluation, a brief psychiatric interview (Primary Care Evaluation of Mental Disorders, PRIME-MD) and completed a battery of questionnaires including the AQLQ(S), the St-Georges Respiratory Questionnaire (SGRQ), and the Psychiatric Symptom Index (PSI).</p> <p>Results</p> <p>There was good internal consistency (Cronbach alpha = 0.936 for the AQLQ(S) total score) and construct validity for the AQLQ(S) (Spearman rho = -0.693 for the SGRQ symptom score and rho = -0.650 for the asthma severity score). There were medium to large correlations between the total score of the AQLQ(S) and the SGRQ symptom score (r = -.693), and PSI total (r = -.619) and subscale scores (including depression, r = -.419; anxiety, r = -.664; anger, r = -.367; cognitive disturbances, r = -.419). A cut-off of 5.1 on the AQLQ(S) emotional function subscale (where 0 = high impairment and 7 = no impairment) had the best discriminative value to distinguish individuals with or without clinically significant psychiatric distress according to the PSI, and a cut-off of 4.7 best distinguished individuals with or without a current psychiatric disorder according to the PRIME-MD.</p> <p>Conclusions</p> <p>Impaired quality of life is associated with psychological distress and psychiatric disorders in individuals with OA. Findings suggest that the AQLQ(S) questionnaire may be used to identify patients with potentially clinically significant levels of psychological distress.</p>http://www.hqlo.com/content/9/1/76Occupational asthmapsychiatric disorderpsychological distressscreeningquality of life
spellingShingle Ghezzo Heberto
L'Archeveque Jocelyne
Lavoie Kim L
Miedinger David
Malo Jean-Luc
Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
Health and Quality of Life Outcomes
Occupational asthma
psychiatric disorder
psychological distress
screening
quality of life
title Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
title_full Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
title_fullStr Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
title_full_unstemmed Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
title_short Identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
title_sort identification of clinically significant psychological distress and psychiatric morbidity by examining quality of life in subjects with occupational asthma
topic Occupational asthma
psychiatric disorder
psychological distress
screening
quality of life
url http://www.hqlo.com/content/9/1/76
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