Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm

Mercury is a toxic substance that is commonly used in skin lightening products. Various effects on humans have been observed, which affect both users and non-users. Many studies reported delayed diagnosis and treatment, even after weeks of hospitalization. The possible reasons are non-specific clin...

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Main Author: Fitri Fareez Ramli
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021-06-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4759
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author Fitri Fareez Ramli
author_facet Fitri Fareez Ramli
author_sort Fitri Fareez Ramli
collection DOAJ
description Mercury is a toxic substance that is commonly used in skin lightening products. Various effects on humans have been observed, which affect both users and non-users. Many studies reported delayed diagnosis and treatment, even after weeks of hospitalization. The possible reasons are non-specific clinical manifestation and lack of awareness and knowledge regarding chronic mercury intoxication secondary to skin lightening products. A thorough history of mercury exposure is crucial. Physical assessment and relevant supporting tests are indicated to establish a diagnosis. Blood and urine mercury levels are an essential examination for diagnosis and monitoring of the progress and response to treatment. The primary treatment is the discontinuation of the skin lightening products. Chelation therapy is not mandatory and is usually indicated for symptomatic patients. The prognosis depends on the duration of the product use, concentration of mercury in the skin product, and the severity of clinical presentation.
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spelling doaj.art-e2e738bc6f684a52aa13929d72ec99332024-03-15T13:44:20ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2021-06-0121310.17305/bjbms.2020.4759Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithmFitri Fareez Ramli0https://orcid.org/0000-0003-4030-7616Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia Mercury is a toxic substance that is commonly used in skin lightening products. Various effects on humans have been observed, which affect both users and non-users. Many studies reported delayed diagnosis and treatment, even after weeks of hospitalization. The possible reasons are non-specific clinical manifestation and lack of awareness and knowledge regarding chronic mercury intoxication secondary to skin lightening products. A thorough history of mercury exposure is crucial. Physical assessment and relevant supporting tests are indicated to establish a diagnosis. Blood and urine mercury levels are an essential examination for diagnosis and monitoring of the progress and response to treatment. The primary treatment is the discontinuation of the skin lightening products. Chelation therapy is not mandatory and is usually indicated for symptomatic patients. The prognosis depends on the duration of the product use, concentration of mercury in the skin product, and the severity of clinical presentation. https://www.bjbms.org/ojs/index.php/bjbms/article/view/4759Mercurycosmeticsskin-lighteningskin-whiteningbleachingnephrotic syndrome
spellingShingle Fitri Fareez Ramli
Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
Biomolecules & Biomedicine
Mercury
cosmetics
skin-lightening
skin-whitening
bleaching
nephrotic syndrome
title Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
title_full Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
title_fullStr Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
title_full_unstemmed Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
title_short Clinical management of chronic mercury intoxication secondary to skin lightening products: A proposed algorithm
title_sort clinical management of chronic mercury intoxication secondary to skin lightening products a proposed algorithm
topic Mercury
cosmetics
skin-lightening
skin-whitening
bleaching
nephrotic syndrome
url https://www.bjbms.org/ojs/index.php/bjbms/article/view/4759
work_keys_str_mv AT fitrifareezramli clinicalmanagementofchronicmercuryintoxicationsecondarytoskinlighteningproductsaproposedalgorithm