Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension

Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension

Objective: To investigate the effects of angiotensin-converting enzyme 2 (ACE2) activation on pulmonary arterial cell apoptosis during pulmonary vascular remodeling associated with pulmonary arterial hypertension (PAH) and to elucidate potential mechanisms related to Hippo signaling. Methods: PAH mo...

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Bibliographic Details
Main Authors: Daole Yan, Gang Li, Yaozhong Zhang, Yinglong Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-08-01
Series:Clinical and Experimental Hypertension
Subjects:
ace2
pah
hippo
apoptosis
vascular remodeling
Online Access:http://dx.doi.org/10.1080/10641963.2019.1583247

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