Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.

Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.

Preparing targeted cells for medical applications from human induced pluripotent stem cells (hiPSCs) using growth factors, compounds, or gene transfer has been challenging. Here, we report that human induced hepatic lineage-oriented stem cells (hiHSCs) were generated and expanded as a new type of hi...

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Bibliographic Details
Main Authors: Tetsuya Ishikawa, Momoko Kobayashi, Satoshi Yanagi, Chika Kato, Ryokichi Takashima, Eiji Kobayashi, Keitaro Hagiwara, Takahiro Ochiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395359?pdf=render

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http://europepmc.org/articles/PMC4395359?pdf=render

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