DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure[S]

DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure[S]

Obesity is the major risk factor for type 2 diabetes, cardiovascular disorders, and many other diseases. Adipose tissue inflammation is frequently associated with obesity and contributes to the morbidity and mortality. Dedicator of cytokinesis 2 (DOCK2) is involved in several inflammatory diseases,...

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Bibliographic Details
Main Authors: Xia Guo, Feifei Li, Zaiyan Xu, Amelia Yin, Hang Yin, Chenxiao Li, Shi-You Chen
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Journal of Lipid Research
Subjects:
dedicator of cytokinesis 2
insulin resistance
macrophage
high-fat diet
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339493

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