Effect of statin treatment on metabolites, lipids and prostanoids in patients with Statin Associated Muscle Symptoms (SAMS).

Effect of statin treatment on metabolites, lipids and prostanoids in patients with Statin Associated Muscle Symptoms (SAMS).

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<h4>Background</h4>Between 5-10% of patients discontinue statin therapy due to statin-associated adverse reactions, primarily statin associated muscle symptoms (SAMS). The absence of a clear clinical phenotype or of biomarkers poses a challenge for diagnosis and management of SAMS. Simil...

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Bibliographic Details
Main Authors: Timothy J Garrett, Michelle A Puchowicz, Edwards A Park, Qingming Dong, Gregory Farage, Richard Childress, Joy Guingab, Claire L Simpson, Saunak Sen, Elizabeth C Brogdon, Logan M Buchanan, Rajendra Raghow, Marshall B Elam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0294498

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