Immunomodulatory meaning of diet and COVID-19
Introduction and objective The latest scientific reports showed that there is a relationship between the state of the gastrointestinal tract and the immune system, and the incidence of COVID-19. Diet can exert an immunomodulatory effect and regulate the immune response of an organism. The aim of the...
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| Format: | Article |
| Language: | English |
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Institute of Rural Health
2022-10-01
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| Series: | Medycyna Ogólna i Nauki o Zdrowiu |
| Subjects: | |
| Online Access: | https://www.monz.pl/Immunomodulatory-meaning-of-diet-and-COVID-19,155414,0,2.html |
| _version_ | 1827989728490684416 |
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| author | Dominika Grońska Monika Kłujsza Aleksandra Pelczar Jolanta Kaszuba-Zwoińska |
| author_facet | Dominika Grońska Monika Kłujsza Aleksandra Pelczar Jolanta Kaszuba-Zwoińska |
| author_sort | Dominika Grońska |
| collection | DOAJ |
| description | Introduction and objective
The latest scientific reports showed that there is a relationship between the state of the gastrointestinal tract and the immune system, and the incidence of COVID-19. Diet can exert an immunomodulatory effect and regulate the immune response of an organism. The aim of the review is to show the effects of immunomodulators contained/supplemented in a diet on the infection SARS-CoV-2 and the course of COVID-19.
Review methods
The literature review was conducted using PubMed, Google Scholar and the Medline database.
Abbreviated description of the state of knowledge
Regular vitamin D supplementation significantly reduces the risk of respiratory infection with SARS-CoV-2; vitamin C may inhibit the expression of the ACE2 receptor in human small alveolar epithelial cells and limit the penetration of SARS-CoV-2; reduced iron levels predispose people to severe COVID-19 symptoms; selenium deficiency may be responsible for a decreased level of antibodies and NK cell cytotoxicity. Aloë vera isolated polysaccharides strengthens the immune system; the quercetin and ellagic acid in combination with virus proteins show potential antiviral activity against SARSCoV-
2. Subsequently, adaptogens, ginger, echinacea and curcumin - showed anti-inflammatory effects. Also, the optimal composition of the gut microbiota improved/maintained the integrity of the lymphoid tissue found in the gastrointestinal tract (GALT) and the functioning of the gut-pulmonary axis.
Summary
Natural immunomodulators may be a relatively safe therapeutic option in patients during the course of COVID-19, but there are still no official recommendations for their practical use in therapy. It should be emphasized that there is a need for further scientific research into the mechanisms of action and efficacy of phytotherapy in the context of the effectiveness of plant-based immunostimulants in alleviating the course of COVID-19 disease. |
| first_indexed | 2024-04-10T00:24:46Z |
| format | Article |
| id | doaj.art-e2f33e355f9a43b0a1641254addeeed1 |
| institution | Directory Open Access Journal |
| issn | 2083-4543 2084-4905 |
| language | English |
| last_indexed | 2024-04-10T00:24:46Z |
| publishDate | 2022-10-01 |
| publisher | Institute of Rural Health |
| record_format | Article |
| series | Medycyna Ogólna i Nauki o Zdrowiu |
| spelling | doaj.art-e2f33e355f9a43b0a1641254addeeed12023-03-15T11:29:49ZengInstitute of Rural HealthMedycyna Ogólna i Nauki o Zdrowiu2083-45432084-49052022-10-0128428629410.26444/monz/155414155414Immunomodulatory meaning of diet and COVID-19Dominika Grońska0https://orcid.org/0000-0002-6393-0630Monika Kłujsza1https://orcid.org/0000-0002-9049-2648Aleksandra Pelczar2https://orcid.org/0000-0002-2760-3309Jolanta Kaszuba-Zwoińska3https://orcid.org/0000-0002-9624-0492Department of Pathophysiology, Collegium Medicum, Jagiellonian University, Kraków, PolandDepartment of Pathophysiology, Collegium Medicum, Jagiellonian University, Kraków, PolandDepartment of Pathophysiology, Collegium Medicum, Jagiellonian University, Kraków, PolandDepartment of Pathophysiology, Collegium Medicum, Jagiellonian University, Kraków, PolandIntroduction and objective The latest scientific reports showed that there is a relationship between the state of the gastrointestinal tract and the immune system, and the incidence of COVID-19. Diet can exert an immunomodulatory effect and regulate the immune response of an organism. The aim of the review is to show the effects of immunomodulators contained/supplemented in a diet on the infection SARS-CoV-2 and the course of COVID-19. Review methods The literature review was conducted using PubMed, Google Scholar and the Medline database. Abbreviated description of the state of knowledge Regular vitamin D supplementation significantly reduces the risk of respiratory infection with SARS-CoV-2; vitamin C may inhibit the expression of the ACE2 receptor in human small alveolar epithelial cells and limit the penetration of SARS-CoV-2; reduced iron levels predispose people to severe COVID-19 symptoms; selenium deficiency may be responsible for a decreased level of antibodies and NK cell cytotoxicity. Aloë vera isolated polysaccharides strengthens the immune system; the quercetin and ellagic acid in combination with virus proteins show potential antiviral activity against SARSCoV- 2. Subsequently, adaptogens, ginger, echinacea and curcumin - showed anti-inflammatory effects. Also, the optimal composition of the gut microbiota improved/maintained the integrity of the lymphoid tissue found in the gastrointestinal tract (GALT) and the functioning of the gut-pulmonary axis. Summary Natural immunomodulators may be a relatively safe therapeutic option in patients during the course of COVID-19, but there are still no official recommendations for their practical use in therapy. It should be emphasized that there is a need for further scientific research into the mechanisms of action and efficacy of phytotherapy in the context of the effectiveness of plant-based immunostimulants in alleviating the course of COVID-19 disease.https://www.monz.pl/Immunomodulatory-meaning-of-diet-and-COVID-19,155414,0,2.htmlvitaminsprobioticsdietmicroelementscovid-19plant immunostimulants |
| spellingShingle | Dominika Grońska Monika Kłujsza Aleksandra Pelczar Jolanta Kaszuba-Zwoińska Immunomodulatory meaning of diet and COVID-19 Medycyna Ogólna i Nauki o Zdrowiu vitamins probiotics diet microelements covid-19 plant immunostimulants |
| title | Immunomodulatory meaning of diet and COVID-19 |
| title_full | Immunomodulatory meaning of diet and COVID-19 |
| title_fullStr | Immunomodulatory meaning of diet and COVID-19 |
| title_full_unstemmed | Immunomodulatory meaning of diet and COVID-19 |
| title_short | Immunomodulatory meaning of diet and COVID-19 |
| title_sort | immunomodulatory meaning of diet and covid 19 |
| topic | vitamins probiotics diet microelements covid-19 plant immunostimulants |
| url | https://www.monz.pl/Immunomodulatory-meaning-of-diet-and-COVID-19,155414,0,2.html |
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