Unexplained recurrent high fever observed in a depressed adolescent

Abstract Background Depressive episodes in adolescents are often accompanied by various physical symptoms, but few studies have explored the association between depression and fever, This case study is the first to report the relationship between unexplained recurrent high fever and depression. Case...

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Main Authors: Xunyi Guo, Yuning Li, Lu Bai, Feng Lin, Jing Chen, Tao Zou
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-024-05705-3
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author Xunyi Guo
Yuning Li
Lu Bai
Feng Lin
Jing Chen
Tao Zou
author_facet Xunyi Guo
Yuning Li
Lu Bai
Feng Lin
Jing Chen
Tao Zou
author_sort Xunyi Guo
collection DOAJ
description Abstract Background Depressive episodes in adolescents are often accompanied by various physical symptoms, but few studies have explored the association between depression and fever, This case study is the first to report the relationship between unexplained recurrent high fever and depression. Case presentation H is a 15 year old adolescent female currently in junior year. 2 + months ago, H gradually felt depressed after a class change. Around the time, the patient suddenly developed chills with no obvious trigger and fever. H was treated with anti-infective and anti-viral treatments all of which did not show significant improvement. No significant abnormality was seen in any of the related examinations. Considering that the patient’s anxiety, depression and somatic symptoms were obvious during the course of the disease, she was given venlafaxine hydrochloride extended-release capsule 75 mg/d; tandospirone citrate capsule 10 mg Bid; alprazolam tablets 0.4 mg qn to improve mood and sleep; supplemented with transcranial repetitive magnetic stimulation therapy 2 times/d; visible light therapy 1 time/d and psychological counseling once. Over the 6 days of treatment, the patient’s body temperature gradually returned to the normal range and her mood improved significantly. Conclusion Depression should be considered a potential cause of unexplained recurrent fevers in adolescents, even when the temperature is significantly outside the normal range.
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spelling doaj.art-e2f57af6c0c643b1b8067baf5b3d97812024-04-21T11:26:18ZengBMCBMC Psychiatry1471-244X2024-04-012411510.1186/s12888-024-05705-3Unexplained recurrent high fever observed in a depressed adolescentXunyi Guo0Yuning Li1Lu Bai2Feng Lin3Jing Chen4Tao Zou5Department of Psychiatry, The Affiliated Hospital of Guizhou Medical UniversityDepartment of Psychiatry, The Affiliated Hospital of Guizhou Medical UniversityDepartment of Clinical Medicine, Guizhou Medical UniversityDepartment of Clinical Medicine, Guizhou Medical UniversityDepartment of Psychiatry, The Affiliated Hospital of Guizhou Medical UniversityDepartment of Psychiatry, The Affiliated Hospital of Guizhou Medical UniversityAbstract Background Depressive episodes in adolescents are often accompanied by various physical symptoms, but few studies have explored the association between depression and fever, This case study is the first to report the relationship between unexplained recurrent high fever and depression. Case presentation H is a 15 year old adolescent female currently in junior year. 2 + months ago, H gradually felt depressed after a class change. Around the time, the patient suddenly developed chills with no obvious trigger and fever. H was treated with anti-infective and anti-viral treatments all of which did not show significant improvement. No significant abnormality was seen in any of the related examinations. Considering that the patient’s anxiety, depression and somatic symptoms were obvious during the course of the disease, she was given venlafaxine hydrochloride extended-release capsule 75 mg/d; tandospirone citrate capsule 10 mg Bid; alprazolam tablets 0.4 mg qn to improve mood and sleep; supplemented with transcranial repetitive magnetic stimulation therapy 2 times/d; visible light therapy 1 time/d and psychological counseling once. Over the 6 days of treatment, the patient’s body temperature gradually returned to the normal range and her mood improved significantly. Conclusion Depression should be considered a potential cause of unexplained recurrent fevers in adolescents, even when the temperature is significantly outside the normal range.https://doi.org/10.1186/s12888-024-05705-3Adolescent depressionHigh feverFever of unknown originStress
spellingShingle Xunyi Guo
Yuning Li
Lu Bai
Feng Lin
Jing Chen
Tao Zou
Unexplained recurrent high fever observed in a depressed adolescent
BMC Psychiatry
Adolescent depression
High fever
Fever of unknown origin
Stress
title Unexplained recurrent high fever observed in a depressed adolescent
title_full Unexplained recurrent high fever observed in a depressed adolescent
title_fullStr Unexplained recurrent high fever observed in a depressed adolescent
title_full_unstemmed Unexplained recurrent high fever observed in a depressed adolescent
title_short Unexplained recurrent high fever observed in a depressed adolescent
title_sort unexplained recurrent high fever observed in a depressed adolescent
topic Adolescent depression
High fever
Fever of unknown origin
Stress
url https://doi.org/10.1186/s12888-024-05705-3
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