Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2020-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-18028-0 |
| _version_ | 1818692327482327040 |
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| author | Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn |
| author_facet | Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn |
| author_sort | Jae-Hyung Jin |
| collection | DOAJ |
| description | Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes. |
| first_indexed | 2024-12-17T12:56:02Z |
| format | Article |
| id | doaj.art-e2f7a6bfdd5b4b528a41782645be312c |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T12:56:02Z |
| publishDate | 2020-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e2f7a6bfdd5b4b528a41782645be312c2022-12-21T21:47:28ZengNature PortfolioNature Communications2041-17232020-08-0111111710.1038/s41467-020-18028-0Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformansJae-Hyung Jin0Kyung-Tae Lee1Joohyeon Hong2Dongpil Lee3Eun-Ha Jang4Jin-Young Kim5Yeonseon Lee6Seung-Heon Lee7Yee-Seul So8Kwang-Woo Jung9Dong-Gi Lee10Eunji Jeong11Minjae Lee12Yu-Byeong Jang13Yeseul Choi14Myung Ha Lee15Ji-Seok Kim16Seong-Ryong Yu17Jin-Tae Choi18Jae-Won La19Haneul Choi20Sun-Woo Kim21Kyung Jin Seo22Yelin Lee23Eun Jung Thak24Jaeyoung Choi25Anna F. Averette26Yong-Hwan Lee27Joseph Heitman28Hyun Ah Kang29Eunji Cheong30Yong-Sun Bahn31Department of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Life Science, College of Natural Science, Chung-Ang UniversitySmart Farm Research Center, Korea Institute of Science and TechnologyDepartments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical CenterDepartment of Agricultural Biotechnology, Seoul National UniversityDepartments of Molecular Genetics and Microbiology, Medicine, and Pharmacology and Cancer Biology, Duke University Medical CenterDepartment of Life Science, College of Natural Science, Chung-Ang UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei UniversityPhosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.https://doi.org/10.1038/s41467-020-18028-0 |
| spellingShingle | Jae-Hyung Jin Kyung-Tae Lee Joohyeon Hong Dongpil Lee Eun-Ha Jang Jin-Young Kim Yeonseon Lee Seung-Heon Lee Yee-Seul So Kwang-Woo Jung Dong-Gi Lee Eunji Jeong Minjae Lee Yu-Byeong Jang Yeseul Choi Myung Ha Lee Ji-Seok Kim Seong-Ryong Yu Jin-Tae Choi Jae-Won La Haneul Choi Sun-Woo Kim Kyung Jin Seo Yelin Lee Eun Jung Thak Jaeyoung Choi Anna F. Averette Yong-Hwan Lee Joseph Heitman Hyun Ah Kang Eunji Cheong Yong-Sun Bahn Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans Nature Communications |
| title | Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
| title_full | Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
| title_fullStr | Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
| title_full_unstemmed | Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
| title_short | Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans |
| title_sort | genome wide functional analysis of phosphatases in the pathogenic fungus cryptococcus neoformans |
| url | https://doi.org/10.1038/s41467-020-18028-0 |
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