The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis.
Sorting nexin 5 (SNX5), a member of sorting nexin family, plays an important role in membrane trafficking, including the retrograde trafficking of the cation independent mannose 6-phosphate receptor (CI-M6PR) and macropinocytosis. Using ESI-LCMS/MS analysis, we confirmed that SNX5 serine 226 is phos...
Main Authors: | Nao Itai, Tsukasa Shimazu, Takayuki Kimura, Issei Ibe, Ryo Yamashita, Yasushi Kaburagi, Taeko Dohi, Takashi Tonozuka, Toshifumi Takao, Atsushi Nishikawa |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6231649?pdf=render |
Similar Items
-
Sorting Nexins in Protein Homeostasis
by: Sara E. Hanley, et al.
Published: (2020-12-01) -
A role for sorting nexin 27 in AMPA receptor trafficking
by: Loo, Li Shen, et al.
Published: (2014) -
Characterization of the First Secreted Sorting Nexin Identified in the <i>Leishmania</i> Protists
by: Olympia Tziouvara, et al.
Published: (2024-04-01) -
Vps501 links sorting nexins to TORC1 regulation in budding yeast
by: Jacob H. Brock, et al.
Published: (2022-12-01) -
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting
by: Ryan C. Gimple, et al.
Published: (2023-03-01)