Bilateral horizontal gaze palsy due to Anti-IgLON5 disease

Purpose: To highlight the eye movement disturbances in anti-IgLON5 disease. Methods: Case report. Results: Anti-IgLON5 is a heterogenous neurodegenerative and autoimmune disease manifested by a variety of signs and symptoms including sleep disorder, bulbar dysfunction, movement disorder, cognitive i...

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Main Author: M Tariq Bhatti, MD
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993622003206
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author M Tariq Bhatti, MD
author_facet M Tariq Bhatti, MD
author_sort M Tariq Bhatti, MD
collection DOAJ
description Purpose: To highlight the eye movement disturbances in anti-IgLON5 disease. Methods: Case report. Results: Anti-IgLON5 is a heterogenous neurodegenerative and autoimmune disease manifested by a variety of signs and symptoms including sleep disorder, bulbar dysfunction, movement disorder, cognitive impairment, and autonomic dysfunction. Conclusions and Importance: Eye movement disturbances (e.g., nystagmus, gaze palsy, slow saccadic velocities) can be a prominent clinical feature of anti-IgLON5 disease.
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spelling doaj.art-e302337e10ff460a94a5ee1600d3507f2022-12-22T03:07:31ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-09-0127101574Bilateral horizontal gaze palsy due to Anti-IgLON5 diseaseM Tariq Bhatti, MD0Departments of Ophthalmology and Neurology, Mayo Clinic College of Medicine, Rochester, MN, USAPurpose: To highlight the eye movement disturbances in anti-IgLON5 disease. Methods: Case report. Results: Anti-IgLON5 is a heterogenous neurodegenerative and autoimmune disease manifested by a variety of signs and symptoms including sleep disorder, bulbar dysfunction, movement disorder, cognitive impairment, and autonomic dysfunction. Conclusions and Importance: Eye movement disturbances (e.g., nystagmus, gaze palsy, slow saccadic velocities) can be a prominent clinical feature of anti-IgLON5 disease.http://www.sciencedirect.com/science/article/pii/S2451993622003206Gaze palsyIgLON5AutoimmunitySleep disorderBulbar dysfunction
spellingShingle M Tariq Bhatti, MD
Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
American Journal of Ophthalmology Case Reports
Gaze palsy
IgLON5
Autoimmunity
Sleep disorder
Bulbar dysfunction
title Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
title_full Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
title_fullStr Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
title_full_unstemmed Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
title_short Bilateral horizontal gaze palsy due to Anti-IgLON5 disease
title_sort bilateral horizontal gaze palsy due to anti iglon5 disease
topic Gaze palsy
IgLON5
Autoimmunity
Sleep disorder
Bulbar dysfunction
url http://www.sciencedirect.com/science/article/pii/S2451993622003206
work_keys_str_mv AT mtariqbhattimd bilateralhorizontalgazepalsyduetoantiiglon5disease