The Role of IL-10 in Malaria: A Double Edged Sword

The Role of IL-10 in Malaria: A Double Edged Sword

IL-10 produced by CD4+ T cells suppresses inflammation by inhibiting T cell functions and the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 cells, but has since been described in IFNγ-producing Tbet+ Th1, FoxP3+ CD4+ regulatory T (Treg) and IL-17-producing...

Full description

Bibliographic Details
Main Authors: Rajiv Kumar, Susanna Ng, Christian Engwerda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
IL-10
malaria
protozoan
T cells
Inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00229/full

Similar Items

Similar Items