Dissecting the <i>Mycobacterium bovis</i> BCG Response to Macrophage Infection to Help Prioritize Targets for Anti-Tuberculosis Drug and Vaccine Discovery

Dissecting the <i>Mycobacterium bovis</i> BCG Response to Macrophage Infection to Help Prioritize Targets for Anti-Tuberculosis Drug and Vaccine Discovery

New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of <i>Mycobacterium tuberculosis</i> after macrophage phagocytosis is a fundamental step in the complex host–pathogen interactions that lead to granuloma formation and disea...

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Bibliographic Details
Main Authors: Jamie Medley, Aaron Goff, Paulo J. G. Bettencourt, Madelaine Dare, Liam Cole, Daire Cantillon, Simon J. Waddell
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vaccines
Subjects:
tuberculosis
<i>Mycobacterium</i>
macrophage
host-pathogen interactions
transcriptomics
BCG
Online Access:https://www.mdpi.com/2076-393X/10/1/113

Internet

https://www.mdpi.com/2076-393X/10/1/113

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