Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases

Abstract Non-small cell lung cancer (NSCLC) metastatic to the brain leptomeninges is rapidly fatal, cannot be biopsied, and cancer cells in the cerebrospinal fluid (CSF) are few; therefore, available tissue samples to develop effective treatments are severely limited. This study aimed to converge si...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Yingmei Li, Dina Polyak, Layton Lamsam, Ian David Connolly, Eli Johnson, Lina Khav Khoeur, Stephanie Andersen, Monica Granucci, Geoff Stanley, Boxiang Liu, Seema Nagpal, Melanie Hayden Gephart
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Nature Portfolio 2021-10-01
Sarja:npj Precision Oncology
Linkit:https://doi.org/10.1038/s41698-021-00228-6