Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases

Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases

Abstract Non-small cell lung cancer (NSCLC) metastatic to the brain leptomeninges is rapidly fatal, cannot be biopsied, and cancer cells in the cerebrospinal fluid (CSF) are few; therefore, available tissue samples to develop effective treatments are severely limited. This study aimed to converge si...

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Bibliographic Details
Main Authors:	Yingmei Li, Dina Polyak, Layton Lamsam, Ian David Connolly, Eli Johnson, Lina Khav Khoeur, Stephanie Andersen, Monica Granucci, Geoff Stanley, Boxiang Liu, Seema Nagpal, Melanie Hayden Gephart
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-10-01
Series:	npj Precision Oncology
Online Access:	https://doi.org/10.1038/s41698-021-00228-6

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