Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways

Amphiregulin regulates odontogenic differentiation of dental pulp stem cells by activation of mitogen-activated protein kinase and the phosphatidylinositol 3-kinase signaling pathways

Abstract Background Human dental pulp stem cells (hDPSCs) have received widespread attention in the fields of tissue engineering and regenerative medicine. Although amphiregulin (AREG) has been shown to play a vital function in the biological processes of various cell types, its effects on DPSCs rem...

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Bibliographic Details
Main Authors:	Junqing Li, Zhihua Wang, Juan Wang, Qian Guo, Yi Fu, Zihan Dai, Minghao Wang, Yu Bai, Xin Liu, Paul R. Cooper, Jiayuan Wu, Wenxi He
Format:	Article
Language:	English
Published:	BMC 2022-07-01
Series:	Stem Cell Research & Therapy
Subjects:	Cell differentiation Signal transduction Tissue regeneration
Online Access:	https://doi.org/10.1186/s13287-022-02971-4

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