Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities
Abstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been growing swiftly worldwide. Patients with background chronic pulmonary inflammations such as asthma or chronic obstructive pulmonary diseases (COPD) are likely to be infected with this virus. Of note, there...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | Cell Communication and Signaling |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12964-022-00982-5 |
| _version_ | 1828156145934532608 |
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| author | Hadi Rajabi Deniz Mortazavi Nur Konyalilar Gizem Tuse Aksoy Sinem Erkan Seval Kubra Korkunc Ozgecan Kayalar Hasan Bayram Reza Rahbarghazi |
| author_facet | Hadi Rajabi Deniz Mortazavi Nur Konyalilar Gizem Tuse Aksoy Sinem Erkan Seval Kubra Korkunc Ozgecan Kayalar Hasan Bayram Reza Rahbarghazi |
| author_sort | Hadi Rajabi |
| collection | DOAJ |
| description | Abstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been growing swiftly worldwide. Patients with background chronic pulmonary inflammations such as asthma or chronic obstructive pulmonary diseases (COPD) are likely to be infected with this virus. Of note, there is an argument that COVID-19 can remain with serious complications like fibrosis or other pathological changes in the pulmonary tissue of patients with chronic diseases. Along with conventional medications, regenerative medicine, and cell-based therapy could be alternative approaches to compensate for organ loss or restore injured sites using different stem cell types. Owing to unique differentiation capacity and paracrine activity, these cells can accelerate the healing procedure. In this review article, we have tried to scrutinize different reports related to the harmful effects of SARS-CoV-2 on patients with asthma and COPD, as well as the possible therapeutic effects of stem cells in the alleviation of post-COVID-19 complications. Video abstract |
| first_indexed | 2024-04-11T23:05:46Z |
| format | Article |
| id | doaj.art-e315a8def9ee444ea991994c46471a64 |
| institution | Directory Open Access Journal |
| issn | 1478-811X |
| language | English |
| last_indexed | 2024-04-11T23:05:46Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Cell Communication and Signaling |
| spelling | doaj.art-e315a8def9ee444ea991994c46471a642022-12-22T03:58:02ZengBMCCell Communication and Signaling1478-811X2022-11-0120111510.1186/s12964-022-00982-5Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunitiesHadi Rajabi0Deniz Mortazavi1Nur Konyalilar2Gizem Tuse Aksoy3Sinem Erkan4Seval Kubra Korkunc5Ozgecan Kayalar6Hasan Bayram7Reza Rahbarghazi8Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineKoç University Research Centre for Translational Medicine (KUTTAM), Koç University School of MedicineStem Cell Research Centre, Tabriz University of Medical SciencesAbstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been growing swiftly worldwide. Patients with background chronic pulmonary inflammations such as asthma or chronic obstructive pulmonary diseases (COPD) are likely to be infected with this virus. Of note, there is an argument that COVID-19 can remain with serious complications like fibrosis or other pathological changes in the pulmonary tissue of patients with chronic diseases. Along with conventional medications, regenerative medicine, and cell-based therapy could be alternative approaches to compensate for organ loss or restore injured sites using different stem cell types. Owing to unique differentiation capacity and paracrine activity, these cells can accelerate the healing procedure. In this review article, we have tried to scrutinize different reports related to the harmful effects of SARS-CoV-2 on patients with asthma and COPD, as well as the possible therapeutic effects of stem cells in the alleviation of post-COVID-19 complications. Video abstracthttps://doi.org/10.1186/s12964-022-00982-5SARS-CoV-2COPDAsthmaStem cellsRegenerative medicine |
| spellingShingle | Hadi Rajabi Deniz Mortazavi Nur Konyalilar Gizem Tuse Aksoy Sinem Erkan Seval Kubra Korkunc Ozgecan Kayalar Hasan Bayram Reza Rahbarghazi Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities Cell Communication and Signaling SARS-CoV-2 COPD Asthma Stem cells Regenerative medicine |
| title | Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities |
| title_full | Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities |
| title_fullStr | Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities |
| title_full_unstemmed | Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities |
| title_short | Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities |
| title_sort | forthcoming complications in recovered covid 19 patients with copd and asthma possible therapeutic opportunities |
| topic | SARS-CoV-2 COPD Asthma Stem cells Regenerative medicine |
| url | https://doi.org/10.1186/s12964-022-00982-5 |
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