Anti-Inflammatory Effects by Pharmacological Inhibition or Knockdown of Fatty Acid Amide Hydrolase in BV2 Microglial Cells

Anti-Inflammatory Effects by Pharmacological Inhibition or Knockdown of Fatty Acid Amide Hydrolase in BV2 Microglial Cells

Fatty acid amide hydrolase (FAAH) has been recognized as a therapeutic target for several neurological diseases because its inhibition can exert neuroprotective and anti-inflammatory effects by boosting the endogenous levels of <i>N</i>-acylethanolamines. However, previous studies have s...

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Bibliographic Details
Main Authors: Mikiei Tanaka, Kazuya Yagyu, Scott Sackett, Yumin Zhang
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
immune cells
central nervous system
<i>N</i>-acylethanolamine
siRNA
serine hydrolase
Online Access:https://www.mdpi.com/2073-4409/8/5/491

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