TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS
HIV infection concurrent with tuberculosis continues to remain an important health problem leading to high fatality rates. This paper analyzes 63 autopsy cases of tuberculosis concurrent with HIV in those who died at the Botkin Clinical Infectious Diseases Hospital in 2012 and 63 cases of the same l...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2014-06-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/92 |
| _version_ | 1826563267290464256 |
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| author | V. A. Zinserling V. V. Svistunov |
| author_facet | V. A. Zinserling V. V. Svistunov |
| author_sort | V. A. Zinserling |
| collection | DOAJ |
| description | HIV infection concurrent with tuberculosis continues to remain an important health problem leading to high fatality rates. This paper analyzes 63 autopsy cases of tuberculosis concurrent with HIV in those who died at the Botkin Clinical Infectious Diseases Hospital in 2012 and 63 cases of the same lesions in those who died at Irkutsk somatic hospitals in 2008-2012. Tuberculosis is shown to be a leading cause of death in 51.6% of the HIV cases in Saint Petersburg. The clinical diagnosis was not verified in some cases. At present there are no absolutely valid methods for the detection of mycobacteria in tissues. The clinical and morphological manifestations of tuberculosis were highly diversified and were mainly generalized forms and did not often fit in the existing classifications. Of great importance were lesions to the central nervous system (22.4%) and intestine (15.3%), which are not virtually recognized clinically. According to the Irkutsk data, there was a preponderance of strains belonging to the Beijing genotype (70%). Assessing the mycobacterial genotype and accounting the whole complex of mixed infections are noted to be important among the promising problems to be studied. |
| first_indexed | 2024-03-12T05:07:13Z |
| format | Article |
| id | doaj.art-e3202f89b7794088af01c595904de3a2 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T10:01:15Z |
| publishDate | 2014-06-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-e3202f89b7794088af01c595904de3a22025-03-02T11:22:18ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-06-0106566092TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTSV. A. Zinserling0V. V. Svistunov1СПбНИИ фтизиопульмонологии; Санкт-Петербургский государственный университет; Городской центр инфекционной патологии на базе ПАО ГУКИБ им. С.П. БоткинаСПбНИИ фтизиопульмонологии; Иркутский государственный медицинский университет; Мунициальная клиническая больница № 1 г. ИркутскаHIV infection concurrent with tuberculosis continues to remain an important health problem leading to high fatality rates. This paper analyzes 63 autopsy cases of tuberculosis concurrent with HIV in those who died at the Botkin Clinical Infectious Diseases Hospital in 2012 and 63 cases of the same lesions in those who died at Irkutsk somatic hospitals in 2008-2012. Tuberculosis is shown to be a leading cause of death in 51.6% of the HIV cases in Saint Petersburg. The clinical diagnosis was not verified in some cases. At present there are no absolutely valid methods for the detection of mycobacteria in tissues. The clinical and morphological manifestations of tuberculosis were highly diversified and were mainly generalized forms and did not often fit in the existing classifications. Of great importance were lesions to the central nervous system (22.4%) and intestine (15.3%), which are not virtually recognized clinically. According to the Irkutsk data, there was a preponderance of strains belonging to the Beijing genotype (70%). Assessing the mycobacterial genotype and accounting the whole complex of mixed infections are noted to be important among the promising problems to be studied.https://www.tibl-journal.com/jour/article/view/92hiv infectiontuberculosismycobacterial genotypespathomorphological patternlesions to the central nervous system and intestine |
| spellingShingle | V. A. Zinserling V. V. Svistunov TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS Туберкулез и болезни лёгких hiv infection tuberculosis mycobacterial genotypes pathomorphological pattern lesions to the central nervous system and intestine |
| title | TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS |
| title_full | TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS |
| title_fullStr | TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS |
| title_full_unstemmed | TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS |
| title_short | TUBERCULOSIS CONCURRENT WITH HIV INFECTION: CLINICAL AND MORPHOLOGICAL ASPECTS |
| title_sort | tuberculosis concurrent with hiv infection clinical and morphological aspects |
| topic | hiv infection tuberculosis mycobacterial genotypes pathomorphological pattern lesions to the central nervous system and intestine |
| url | https://www.tibl-journal.com/jour/article/view/92 |
| work_keys_str_mv | AT vazinserling tuberculosisconcurrentwithhivinfectionclinicalandmorphologicalaspects AT vvsvistunov tuberculosisconcurrentwithhivinfectionclinicalandmorphologicalaspects |