Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection
<p>Abstract</p> <p>Lung resection is the mainstay of treatment in patients with early stage non-small cell lung cancer. However, lung cancer patients often suffer from comorbidities and the respiratory reserve should be carefully evaluated preoperatively in order to avoid postopera...
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| Format: | Article |
| Language: | English |
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Mattioli 1885
2010-06-01
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| Series: | Multidisciplinary Respiratory Medicine |
| Subjects: | |
| Online Access: | http://www.mrmjournal.com/content/5/3/188 |
| _version_ | 1827264210141184000 |
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| author | Papageorgiou Chrysovalantis V Antoniou Dimosthenis Kaltsakas Georgios Koulouris Nikolaos G |
| author_facet | Papageorgiou Chrysovalantis V Antoniou Dimosthenis Kaltsakas Georgios Koulouris Nikolaos G |
| author_sort | Papageorgiou Chrysovalantis V |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Lung resection is the mainstay of treatment in patients with early stage non-small cell lung cancer. However, lung cancer patients often suffer from comorbidities and the respiratory reserve should be carefully evaluated preoperatively in order to avoid postoperative complications. Forced expiratory volume in 1 second (FEV<sub>1</sub>) is considered to be an index that depicts the patient's respiratory efficacy and its prediction has a key role in the preoperative evaluation of lung cancer patients with impaired lung function. Prediction of postoperative FEV<sub>1 </sub>is currently possible with the use of perfusion radionuclide lung scanning.</p> <p>Quantitative CT is the analysis of data acquired during normal chest CT scan using the system's software. By applying a dual threshold of -500 to -910 Hounsfield Units, functional lung volumes are estimated and postoperative FEV<sub>1 </sub>can be predicted by reducing the preoperative measurement by the fraction of the part to be resected.</p> <p>Studies have shown that preoperative predictions correlate well with the actual postoperative measurements. Additionally, quantitative CT results are in good agreement with perfusion scintigraphy predictions. Newer radiological techniques such as perfusion MRI and co-registered SPECT/CT have also been used in the preoperative evaluation with similar results.</p> <p>In conclusion, chest CT which is obligatory for staging, can be used for quantitative analysis of the already available data. It is technically simple, providing an accurate prediction of postoperative FEV<sub>1</sub>. Thus, quantitative CT appears to be a useful tool in the preoperative evaluation of lung cancer patients undergoing lung resection.</p> |
| first_indexed | 2024-03-07T17:16:13Z |
| format | Article |
| id | doaj.art-e321b49b123c4815b1eb9d4ca0fd0ada |
| institution | Directory Open Access Journal |
| issn | 2049-6958 |
| language | English |
| last_indexed | 2025-03-22T03:42:26Z |
| publishDate | 2010-06-01 |
| publisher | Mattioli 1885 |
| record_format | Article |
| series | Multidisciplinary Respiratory Medicine |
| spelling | doaj.art-e321b49b123c4815b1eb9d4ca0fd0ada2024-04-28T11:58:38ZengMattioli 1885Multidisciplinary Respiratory Medicine2049-69582010-06-015318819310.1186/2049-6958-5-3-188Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resectionPapageorgiou Chrysovalantis VAntoniou DimosthenisKaltsakas GeorgiosKoulouris Nikolaos G<p>Abstract</p> <p>Lung resection is the mainstay of treatment in patients with early stage non-small cell lung cancer. However, lung cancer patients often suffer from comorbidities and the respiratory reserve should be carefully evaluated preoperatively in order to avoid postoperative complications. Forced expiratory volume in 1 second (FEV<sub>1</sub>) is considered to be an index that depicts the patient's respiratory efficacy and its prediction has a key role in the preoperative evaluation of lung cancer patients with impaired lung function. Prediction of postoperative FEV<sub>1 </sub>is currently possible with the use of perfusion radionuclide lung scanning.</p> <p>Quantitative CT is the analysis of data acquired during normal chest CT scan using the system's software. By applying a dual threshold of -500 to -910 Hounsfield Units, functional lung volumes are estimated and postoperative FEV<sub>1 </sub>can be predicted by reducing the preoperative measurement by the fraction of the part to be resected.</p> <p>Studies have shown that preoperative predictions correlate well with the actual postoperative measurements. Additionally, quantitative CT results are in good agreement with perfusion scintigraphy predictions. Newer radiological techniques such as perfusion MRI and co-registered SPECT/CT have also been used in the preoperative evaluation with similar results.</p> <p>In conclusion, chest CT which is obligatory for staging, can be used for quantitative analysis of the already available data. It is technically simple, providing an accurate prediction of postoperative FEV<sub>1</sub>. Thus, quantitative CT appears to be a useful tool in the preoperative evaluation of lung cancer patients undergoing lung resection.</p>http://www.mrmjournal.com/content/5/3/188Lung cancerlung resectionpredicted postoperative FEV<sub>1</sub>quantitative CT |
| spellingShingle | Papageorgiou Chrysovalantis V Antoniou Dimosthenis Kaltsakas Georgios Koulouris Nikolaos G Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection Multidisciplinary Respiratory Medicine Lung cancer lung resection predicted postoperative FEV<sub>1</sub> quantitative CT |
| title | Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection |
| title_full | Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection |
| title_fullStr | Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection |
| title_full_unstemmed | Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection |
| title_short | Role of quantitative CT in predicting postoperative FEV<sub>1 </sub>and chronic dyspnea in patients undergoing lung resection |
| title_sort | role of quantitative ct in predicting postoperative fev sub 1 sub and chronic dyspnea in patients undergoing lung resection |
| topic | Lung cancer lung resection predicted postoperative FEV<sub>1</sub> quantitative CT |
| url | http://www.mrmjournal.com/content/5/3/188 |
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