ω-3和ω-6多不饱和脂肪酸改善轻度认知障碍机制的研究进展 Progress on the mechanism of ω-3 and ω-6 polyunsaturated fatty acids in improving mild cognitive impairment

ω-3和ω-6多不饱和脂肪酸改善轻度认知障碍机制的研究进展 Progress on the mechanism of ω-3 and ω-6 polyunsaturated fatty acids in improving mild cognitive impairment

近年来，轻度认知障碍(Mild cognitive impairment, MCI)作为阿尔茨海默病（Alzheimer’s disease,AD）的一个早期症状引发关注，对其进行早期干预具有积极意义。现有人群实验、动物实验及细胞实验多方面研究表明，多不饱和脂肪酸(PUFAs)中的ω-3多不饱和脂肪酸（ω-3 PUFAs）可以改善炎症反应，影响轻度认知障碍的发生发展。但ω-6多不饱和脂肪酸（ω-6 PUFAs）的相关代谢产物既包含抗炎物质，又有促炎物质，机制较为复杂，目前研究具有争议性。综述了两种多不饱和脂肪酸对轻度认知障碍作用的机制，探讨饮食营养对改善轻度认知障碍的意义，为多不饱和脂肪酸改善...

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Bibliographic Details
Main Author:	刘佳欣，付朝旭，许妍姬 LIU Jiaxin， FU Chaoxu， XU Yanji
Format:	Article
Language:	English
Published:	中粮工科（西安）国际工程有限公司 2022-04-01
Series:	Zhongguo youzhi
Subjects:	ω-3多不饱和脂肪酸；ω-6多不饱和脂肪酸；轻度认知障碍；神经系统 ω-3 polyunsaturated fatty acids; ω-6 polyunsaturated fatty acids；mild cognitive impairment; nervous system
Online Access:	http://tg.chinaoils.cn/ch/reader/create_pdf.aspx?file_no=20220415&year_id=2022&quarter_id=4&falg=1

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