Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island
Introduction: Endometriosis is a female disease that affects 5–10% of women of childbearing age, with predominantly pelvic manifestations. It is currently declared as a public health priority in France. Thoracic endometriosis syndrome (TES) is the most common extra-pelvic manifestation. Objective: T...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/17/5578 |
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| author | Moustapha Agossou Bruno-Gilbert Sanchez Paul-Henri Alauzen Maud Olivier Elsa Cécilia-Joseph Ludivine Chevallier Mehdi Jean-Laurent Aude Aline-Fardin Moustapha Dramé Nicolas Venissac |
| author_facet | Moustapha Agossou Bruno-Gilbert Sanchez Paul-Henri Alauzen Maud Olivier Elsa Cécilia-Joseph Ludivine Chevallier Mehdi Jean-Laurent Aude Aline-Fardin Moustapha Dramé Nicolas Venissac |
| author_sort | Moustapha Agossou |
| collection | DOAJ |
| description | Introduction: Endometriosis is a female disease that affects 5–10% of women of childbearing age, with predominantly pelvic manifestations. It is currently declared as a public health priority in France. Thoracic endometriosis syndrome (TES) is the most common extra-pelvic manifestation. Objective: The objective of this study was to describe the epidemiological and clinical characteristics, and outcomes of patients with TES in Martinique. Patients and Methods: We performed a descriptive, retrospective study including all patients managed at the University Hospital of Martinique for TES between 1 January 2004 and 31 December 2020. Results: During the study period, we identified 479 cases of pneumothorax, of which 212 were women (44%). Sixty-three patients (30% of all female pneumothorax) were catamenial pneumothorax (CP) including 49 pneumothoraxes alone (78% of catamenial pneumothorax) and 14 hemopneumothorax (22% of catamenial pneumothorax). There were 71 cases of TES, including 49 pneumothoraxes (69%), 14 hemopneumothoraxes (20%) and 8 hemothorax (11%). The annual incidence of TES was 1.1 cases/100,000 inhabitants. The prevalence of TES was 1.2/1000 women aged from 15 to 45 years and the annual incidence of TES for this group was 6.9/100,000. The annual incidence of CP was 1 case/100,000 inhabitants. The average age at diagnosis was 36 ± 6 years. Eight patients (11%) had no prior diagnosis of pelvic endometriosis (PE). The mean age at pelvic endometriosis diagnosis was 29 ± 6 years. The mean time from symptom onset to diagnosis was 24 ± 50 weeks, and 53 ± 123 days from diagnosis to surgery. Thirty-two patients (47%) had prior abdominopelvic surgery. Seventeen patients (24%) presented other extra-pelvic localizations. When it came to management, 69/71 patients (97%) underwent surgery. Diaphragmatic nodules or perforations were found in 68/69 patients (98.5%). Histological confirmation was obtained in 55/65 patients who underwent resection (84.6%). Forty-four patients (62%) experienced recurrence. The mean time from the initial treatment to recurrence was 20 ± 33 months. The recurrence rate was 16/19 (84.2%) in patients who received medical therapy only, 11/17 (64.7%) in patients treated by surgery alone, and 17/31 (51.8%) in patients treated with surgery and medical therapy (<i>p</i> = 0.03). Conclusions: We observed a very high incidence of TES in Martinique. The factors associated with this high incidence in this specific geographical area remain to be elucidated. The frequency of recurrence was lower in patients who received both hormone therapy and surgery. |
| first_indexed | 2024-03-10T23:19:56Z |
| format | Article |
| id | doaj.art-e326ab3c39bd48359c8a46c632418fce |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T23:19:56Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e326ab3c39bd48359c8a46c632418fce2023-11-19T08:22:33ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011217557810.3390/jcm12175578Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies IslandMoustapha Agossou0Bruno-Gilbert Sanchez1Paul-Henri Alauzen2Maud Olivier3Elsa Cécilia-Joseph4Ludivine Chevallier5Mehdi Jean-Laurent6Aude Aline-Fardin7Moustapha Dramé8Nicolas Venissac9Department of Respiratory Medicine, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Thoracic and Cardiovascular Surgery, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Respiratory Medicine, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Thoracic and Cardiovascular Surgery, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Medical Information, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Gynecology and Obstetrics, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Gynecology and Obstetrics, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Pathology, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Clinical Research and Innovation, CHU of Martinique, 97261 Fort-de-France, FranceDepartment of Thoracic Surgery, CHRU of Lille, 59000 Lille, FranceIntroduction: Endometriosis is a female disease that affects 5–10% of women of childbearing age, with predominantly pelvic manifestations. It is currently declared as a public health priority in France. Thoracic endometriosis syndrome (TES) is the most common extra-pelvic manifestation. Objective: The objective of this study was to describe the epidemiological and clinical characteristics, and outcomes of patients with TES in Martinique. Patients and Methods: We performed a descriptive, retrospective study including all patients managed at the University Hospital of Martinique for TES between 1 January 2004 and 31 December 2020. Results: During the study period, we identified 479 cases of pneumothorax, of which 212 were women (44%). Sixty-three patients (30% of all female pneumothorax) were catamenial pneumothorax (CP) including 49 pneumothoraxes alone (78% of catamenial pneumothorax) and 14 hemopneumothorax (22% of catamenial pneumothorax). There were 71 cases of TES, including 49 pneumothoraxes (69%), 14 hemopneumothoraxes (20%) and 8 hemothorax (11%). The annual incidence of TES was 1.1 cases/100,000 inhabitants. The prevalence of TES was 1.2/1000 women aged from 15 to 45 years and the annual incidence of TES for this group was 6.9/100,000. The annual incidence of CP was 1 case/100,000 inhabitants. The average age at diagnosis was 36 ± 6 years. Eight patients (11%) had no prior diagnosis of pelvic endometriosis (PE). The mean age at pelvic endometriosis diagnosis was 29 ± 6 years. The mean time from symptom onset to diagnosis was 24 ± 50 weeks, and 53 ± 123 days from diagnosis to surgery. Thirty-two patients (47%) had prior abdominopelvic surgery. Seventeen patients (24%) presented other extra-pelvic localizations. When it came to management, 69/71 patients (97%) underwent surgery. Diaphragmatic nodules or perforations were found in 68/69 patients (98.5%). Histological confirmation was obtained in 55/65 patients who underwent resection (84.6%). Forty-four patients (62%) experienced recurrence. The mean time from the initial treatment to recurrence was 20 ± 33 months. The recurrence rate was 16/19 (84.2%) in patients who received medical therapy only, 11/17 (64.7%) in patients treated by surgery alone, and 17/31 (51.8%) in patients treated with surgery and medical therapy (<i>p</i> = 0.03). Conclusions: We observed a very high incidence of TES in Martinique. The factors associated with this high incidence in this specific geographical area remain to be elucidated. The frequency of recurrence was lower in patients who received both hormone therapy and surgery.https://www.mdpi.com/2077-0383/12/17/5578endometriosisthoracic endometriosis syndromecatamenial pneumothoraxhemothoraxblack people |
| spellingShingle | Moustapha Agossou Bruno-Gilbert Sanchez Paul-Henri Alauzen Maud Olivier Elsa Cécilia-Joseph Ludivine Chevallier Mehdi Jean-Laurent Aude Aline-Fardin Moustapha Dramé Nicolas Venissac Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island Journal of Clinical Medicine endometriosis thoracic endometriosis syndrome catamenial pneumothorax hemothorax black people |
| title | Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island |
| title_full | Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island |
| title_fullStr | Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island |
| title_full_unstemmed | Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island |
| title_short | Thoracic Endometriosis Syndrome (TES) in Martinique, a French West Indies Island |
| title_sort | thoracic endometriosis syndrome tes in martinique a french west indies island |
| topic | endometriosis thoracic endometriosis syndrome catamenial pneumothorax hemothorax black people |
| url | https://www.mdpi.com/2077-0383/12/17/5578 |
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