Time-resolved spectroscopic and electrophysiological data reveal insights in the gating mechanism of anion channelrhodopsin
Dreier et al. reports that the anion channelrhodopsin GtACR1 does not undergo a syn-cycle (light adapted ground state) and thus has a more efficient channel behaviour than CrChR2. They propose that constructing variants lacking syn-cycle could optimize channelrhodopsin for optogenetic applications.
| Автори: | , , , , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Nature Portfolio
2021-05-01
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| Серія: | Communications Biology |
| Онлайн доступ: | https://doi.org/10.1038/s42003-021-02101-5 |