Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model

Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model

The neuromuscular junction (NMJ) mediates neural control of skeletal muscle fibers. Neurotrophic signaling, specifically brain derived neurotrophic factor (BDNF) acting through its high-affinity tropomyosin related kinase B (TrkB) receptor is known to improve neuromuscular transmission. BDNF/TrkB si...

Full description

Bibliographic Details
Main Authors:	Matthew J. Fogarty, Obaid U. Khurram, Carlos B. Mantilla, Gary C. Sieck
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	diaphragm muscle neuromuscular junction neuromuscular transmission failure neurotrophins genetic models
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.1025463/full

Similar Items

Estimation of the diaphragm neuromuscular efficiency index in mechanically ventilated critically ill patients
by: Diana Jansen, et al.
Published: (2018-09-01)

Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats
by: Matthew J. Fogarty, et al.
Published: (2024-03-01)

MG53 Preserves Neuromuscular Junction Integrity and Alleviates ALS Disease Progression
by: Jianxun Yi, et al.
Published: (2021-09-01)

Effects of hydrocortisone-presensitized sugammadex on recovery from neuromuscular blockade induced by rocuronium: a rodent in vivo study
by: Hey-Ran Choi, et al.
Published: (2022-04-01)

Unraveling the causes of sarcopenia: Roles of neuromuscular junction impairment and mitochondrial dysfunction
by: Yanmei Miao, et al.
Published: (2024-01-01)

Autophagy markers LC3 and p62 in aging lumbar motor neurons
by: Sepideh Jahanian, et al.
Published: (2024-09-01)

Potentiation Effects of Acetylcholine at Neuromuscular Junction by Ranitidine
by: Abdul Azeem , Akbar Waheed , Sidra Mumal , Salman Bakhtiar , Jawaria Iftikhar , Talal Zafar
Published: (2021-12-01)

Motoneuron Wnts regulate neuromuscular junction development
by: Chengyong Shen, et al.
Published: (2018-08-01)

Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin
by: Cornelia Roesl, et al.
Published: (2021-10-01)

Classical and Unexpected Effects of Ultra-Micronized PEA in Neuromuscular Function
by: Pierangelo Cifelli, et al.
Published: (2022-05-01)

An Overview of Mitochondrial Protein Defects in Neuromuscular Diseases
by: Federica Marra, et al.
Published: (2021-11-01)

Myasthenia gravis in clinical practice
by: Eduardo de Paula Estephan, et al.
Published: (2022-08-01)

Comparison of onset of neuromuscular blockade with electromyographic and acceleromyographic monitoring: a prospective clinical trial
by: Harold E. Chaves-Cardona, et al.
Published: (2023-07-01)

A surgeon′s assessment of inadequate neuromuscular antagonism in a case of prolonged neuromuscular blockade
by: James J Lamberg, et al.
Published: (2013-01-01)

NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
by: Erin C. Bailey, et al.
Published: (2019-08-01)

Timeline of hypoglossal motor neuron death and intrinsic tongue muscle denervation in high-copy number SOD1G93A mice
by: Matthew J. Fogarty, et al.
Published: (2024-07-01)

A novel synaptic plasticity rule explains homeostasis of neuromuscular transmission
by: Gilles Ouanounou, et al.
Published: (2016-05-01)

Effects of Mechanical Vibration in Neuromuscular Junctions and Fiber Type of the Soleus Muscle of Oophorectomized Wistar Rats
by: Ana Luiza Peretti, et al.

αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish
by: Matthew J. Rybin, et al.
Published: (2020-03-01)

Neuromuscular transmission /
by: Booij, Leo H. D. J.
Published: (1996)

Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission
by: Maria Nicol Colombo, et al.
Published: (2019-08-01)

Neuromuscular Activity Induces Paracrine Signaling and Triggers Axonal Regrowth after Injury in Microfluidic Lab-On-Chip Devices
by: Julia Sala-Jarque, et al.
Published: (2020-01-01)

Association of regular aerobic exercises and neuromuscular junction variants with incidence of frailty: an analysis of the Chinese Longitudinal Health and Longevity Survey
by: Yu‐Jie Zhang, et al.
Published: (2021-04-01)

Muscle‐restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down‐regulation of myogenin at the neuromuscular junction
by: Hsin‐Hsiung Chen, et al.
Published: (2018-08-01)

Bloqueio neuromuscular residual após o uso de rocurônio ou cisatracúrio Bloqueo neuromuscular residual después del uso de rocuronio o cisatracúrio Residual neuromuscular block after rocuronium or cisatracurium
by: Bruno Salomé de Morais, et al.
Published: (2005-12-01)

Management of patients with neuromuscular disease /
by: Bach, John R., 1950-
Published: (c200)

Functional regeneration of the murine neuromuscular synapse relies on long-lasting morphological adaptations
by: Francisca Bermedo-García, et al.
Published: (2022-07-01)

Neuromuscular interaction is required for neurotrophins-mediated locomotor recovery following treadmill training in rat spinal cord injury
by: Qinfeng Wu, et al.
Published: (2016-05-01)

Phonomyography on Perioperative Neuromuscular Monitoring: An Overview
by: Yanjie Dong, et al.
Published: (2022-03-01)

Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction
by: Qi Wang, et al.
Published: (2018-06-01)

Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging
by: Jacqueline A Larouche, et al.
Published: (2021-07-01)

Intraoperative Monitoring of Neuromuscular Blockade
by: Cyrus Motamed
Published: (2023-05-01)

Investigating Effects of eugenol on nerve conduction and synaptic transmission at neuromuscular junction in an amphibian
by: Christa M. Saelinger, et al.
Published: (2019-04-01)

Age-Related Homeostatic Plasticity at Rodent Neuromuscular Junctions
by: Yizhi Li, et al.
Published: (2024-10-01)

TIGAR deficiency enhances skeletal muscle thermogenesis by increasing neuromuscular junction cholinergic signaling
by: Yan Tang, et al.
Published: (2022-03-01)

Neuromuscular blockade monitoring in pediatric patients
by: Zehra Serpil Ustalar Ozgen
Published: (2024-10-01)

Diagnosing Neuromuscular Diseases
by: Alberto L. Dubrovsky
Published: (2018-08-01)

Cortactin interacts with αDystrobrevin-1 and regulates murine neuromuscular junction morphology
by: Teresa De Cicco, et al.
Published: (2024-06-01)

THE RISK ASSESSMENT OF THE RESIDUAL NEUROMUSCULAR BLOCKADE UNDER LAPAROSCOPIC OPERATIVE INTERVENTIONS
by: D. A. Kurenkov, et al.
Published: (2017-11-01)

Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
by: Kamilla Pedersen, et al.
Published: (2022-12-01)