Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution

Bartter syndrome is a rare autosomal recessive disorder characterized by hypokalaemia. Hypokalaemia is defined as low serum potassium concentration ˂3.5 mmol/L, which may lead to arrhythmia and death if left untreated. The aim of this case report was to normalize serum potassium concentration withou...

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Main Authors: Salman Alasfour, Haya S Alfailakawi, Yousif A Shamsaldeen
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X211019789
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author Salman Alasfour
Haya S Alfailakawi
Yousif A Shamsaldeen
author_facet Salman Alasfour
Haya S Alfailakawi
Yousif A Shamsaldeen
author_sort Salman Alasfour
collection DOAJ
description Bartter syndrome is a rare autosomal recessive disorder characterized by hypokalaemia. Hypokalaemia is defined as low serum potassium concentration ˂3.5 mmol/L, which may lead to arrhythmia and death if left untreated. The aim of this case report was to normalize serum potassium concentration without the need for intravenous intervention. A 5-month-old male of 2.7 kg body weight diagnosed with Bartter syndrome was admitted to the general paediatric ward with acute severe hypokalaemia and urinary tract infection. The main challenge was the inability to administer drugs through intravenous route due to compromised body size. Therefore, we shifted the route of administration to the nasogastric tube/oral route. A total of 2 mL of concentrated intravenous potassium chloride (4 mEq potassium) were dissolved in distilled water and administered through nasogastric tube. Serum potassium concentration was rapidly normalized, which culminated in patient discharge. In conclusion, shifting drug administration from intravenous to oral route in a paediatric patient with Bartter syndrome includes numerous advantages such as patient convenience, minimized risk of cannula-induced infection, and reduced nurse workload.
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spelling doaj.art-e32c7d92355c4321bb6f2e3157f4e5d62022-12-21T20:20:24ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2021-05-01910.1177/2050313X211019789Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solutionSalman Alasfour0Haya S Alfailakawi1Yousif A Shamsaldeen2Paediatric Department, Al Adan Hospital, Ahmadi Medical Governorate, Hadiya, KuwaitAl Adan Paediatric Pharmacy, Kuwait-Al Adan Joint Hospital, Kuwait Hospital, Sabah Al Salem, KuwaitSt. George’s University of London, Cranmer Terrace, Tooting, LondonBartter syndrome is a rare autosomal recessive disorder characterized by hypokalaemia. Hypokalaemia is defined as low serum potassium concentration ˂3.5 mmol/L, which may lead to arrhythmia and death if left untreated. The aim of this case report was to normalize serum potassium concentration without the need for intravenous intervention. A 5-month-old male of 2.7 kg body weight diagnosed with Bartter syndrome was admitted to the general paediatric ward with acute severe hypokalaemia and urinary tract infection. The main challenge was the inability to administer drugs through intravenous route due to compromised body size. Therefore, we shifted the route of administration to the nasogastric tube/oral route. A total of 2 mL of concentrated intravenous potassium chloride (4 mEq potassium) were dissolved in distilled water and administered through nasogastric tube. Serum potassium concentration was rapidly normalized, which culminated in patient discharge. In conclusion, shifting drug administration from intravenous to oral route in a paediatric patient with Bartter syndrome includes numerous advantages such as patient convenience, minimized risk of cannula-induced infection, and reduced nurse workload.https://doi.org/10.1177/2050313X211019789
spellingShingle Salman Alasfour
Haya S Alfailakawi
Yousif A Shamsaldeen
Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
SAGE Open Medical Case Reports
title Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
title_full Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
title_fullStr Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
title_full_unstemmed Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
title_short Correcting hypokalaemia in a paediatric patient with Bartter syndrome through oral dose of potassium chloride intravenous solution
title_sort correcting hypokalaemia in a paediatric patient with bartter syndrome through oral dose of potassium chloride intravenous solution
url https://doi.org/10.1177/2050313X211019789
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