Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by <i>Candida albicans</i>

Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by <i>Candida albicans</i>

Clinical use of 4-Allylpyrocatechol (APC), a potential antifungal agent from <i>Piper betle</i>, is limited because of its low water solubility. The current study explores the development of the self-nanoemulsifying drug delivery system (SNEDDS) containing APC (APC-SNEDDS) to enhance APC...

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Bibliographic Details
Main Authors: Siriporn Okonogi, Pimpak Phumat, Sakornrat Khongkhunthian, Pisaisit Chaijareenont, Thomas Rades, Anette Müllertz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
SNEDDS
4-allylpyrocatechol
solubility enhancement
antifungal activity
oral infections
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/1999-4923/13/2/167

Internet

https://www.mdpi.com/1999-4923/13/2/167

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