Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions
Background: Eosinophilic gastrointestinal disorders (EGID) are uncommon. In Colombia there are no studies in the pediatric population. Objective: To describe the epidemiological, clinical and diagnostic characteristics of a pediatric population with EGID. Methods: Observational, retrospective stud...
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| Format: | Article |
| Language: | English |
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Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2018-07-01
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| Series: | Revista Alergia México |
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| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/354 |
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| author | Luisa Holguín Carolina Gallego-Yépes Yuliana Toro Libia Susana Díez-Zuluaga José Mopan Carlos Chinchilla |
| author_facet | Luisa Holguín Carolina Gallego-Yépes Yuliana Toro Libia Susana Díez-Zuluaga José Mopan Carlos Chinchilla |
| author_sort | Luisa Holguín |
| collection | DOAJ |
| description | Background: Eosinophilic gastrointestinal disorders (EGID) are uncommon. In Colombia there are no studies in the pediatric population.
Objective: To describe the epidemiological, clinical and diagnostic characteristics of a pediatric population with EGID.
Methods: Observational, retrospective study in children aged between 0 and 12 years, assessed in three high complexity hospitals in Medellín, Colombia, between 2010 and 2015.
Results: Out of 151 children, 74 (49%) had eosinophilic esophagitis, 35 (23.2%) had eosinophilic gastritis, 20 (13.2%), eosinophilic duodenitis, and 65 (43%) eosinophilic ileitis or colitis; 60.9% were males, and median age was 5 years; 66.9% had a history of allergic disease, and 78.8% had involvement of a single segment of the gastrointestinal tract. Main symptoms were abdominal pain and vomiting. Maximum eosinophil count per high power field (HPF) in the esophagus, stomach, duodenum, ileum and colon was 34, 21, 42, 45 and 60, respectively. Peripheral eosinophilia was more common in patients with esophageal and stomach involvement. The most sensitizing foods were egg, milk, shrimp, wheat and chicken. Proton pump inhibitors, steroids or immunosuppressants, as well as food-exclusion diets were used.
Conclusions: EGID can compromise multiple segments, and its symptoms are unspecific; multidisciplinary management is required. |
| first_indexed | 2024-03-12T19:39:52Z |
| format | Article |
| id | doaj.art-e3327f5d94374009a12fb3d5d96fdee1 |
| institution | Directory Open Access Journal |
| issn | 0002-5151 2448-9190 |
| language | English |
| last_indexed | 2024-03-12T19:39:52Z |
| publishDate | 2018-07-01 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| record_format | Article |
| series | Revista Alergia México |
| spelling | doaj.art-e3327f5d94374009a12fb3d5d96fdee12023-08-02T03:55:48ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902018-07-0165214815910.29262/ram.v65i2.354242Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutionsLuisa Holguín0Carolina Gallego-Yépes1Yuliana Toro2Libia Susana Díez-Zuluaga3José Mopan4Carlos Chinchilla5Universidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaUniversidad de AntioquiaBackground: Eosinophilic gastrointestinal disorders (EGID) are uncommon. In Colombia there are no studies in the pediatric population. Objective: To describe the epidemiological, clinical and diagnostic characteristics of a pediatric population with EGID. Methods: Observational, retrospective study in children aged between 0 and 12 years, assessed in three high complexity hospitals in Medellín, Colombia, between 2010 and 2015. Results: Out of 151 children, 74 (49%) had eosinophilic esophagitis, 35 (23.2%) had eosinophilic gastritis, 20 (13.2%), eosinophilic duodenitis, and 65 (43%) eosinophilic ileitis or colitis; 60.9% were males, and median age was 5 years; 66.9% had a history of allergic disease, and 78.8% had involvement of a single segment of the gastrointestinal tract. Main symptoms were abdominal pain and vomiting. Maximum eosinophil count per high power field (HPF) in the esophagus, stomach, duodenum, ileum and colon was 34, 21, 42, 45 and 60, respectively. Peripheral eosinophilia was more common in patients with esophageal and stomach involvement. The most sensitizing foods were egg, milk, shrimp, wheat and chicken. Proton pump inhibitors, steroids or immunosuppressants, as well as food-exclusion diets were used. Conclusions: EGID can compromise multiple segments, and its symptoms are unspecific; multidisciplinary management is required.http://revistaalergia.mx/ojs/index.php/ram/article/view/354esofagitis eosinofílicagastroenteritis eosinofílicacolitis eosinofílicaalergia alimentaria |
| spellingShingle | Luisa Holguín Carolina Gallego-Yépes Yuliana Toro Libia Susana Díez-Zuluaga José Mopan Carlos Chinchilla Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions Revista Alergia México esofagitis eosinofílica gastroenteritis eosinofílica colitis eosinofílica alergia alimentaria |
| title | Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions |
| title_full | Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions |
| title_fullStr | Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions |
| title_full_unstemmed | Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions |
| title_short | Epidemiological, clinical and diagnostic characterization of children with eosinophilic gastroenteropathy. A retrospective study of three high complexity health institutions |
| title_sort | epidemiological clinical and diagnostic characterization of children with eosinophilic gastroenteropathy a retrospective study of three high complexity health institutions |
| topic | esofagitis eosinofílica gastroenteritis eosinofílica colitis eosinofílica alergia alimentaria |
| url | http://revistaalergia.mx/ojs/index.php/ram/article/view/354 |
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