Dyslexia on a continuum: A complex network approach.
We investigated the efficacy of graph-theoretic metrics of task-related functional brain connectivity in predicting reading difficulty and explored the hypothesis that task conditions emphasizing audiovisual integration would be especially diagnostic of reading difficulty. An fMRI study was conducte...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0208923 |
| _version_ | 1818985780398260224 |
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| author | Erica S Edwards Kali Burke James R Booth Chris McNorgan |
| author_facet | Erica S Edwards Kali Burke James R Booth Chris McNorgan |
| author_sort | Erica S Edwards |
| collection | DOAJ |
| description | We investigated the efficacy of graph-theoretic metrics of task-related functional brain connectivity in predicting reading difficulty and explored the hypothesis that task conditions emphasizing audiovisual integration would be especially diagnostic of reading difficulty. An fMRI study was conducted in which 24 children (8 to 14 years old) who were previously diagnosed with dyslexia completed a rhyming judgment task under three presentation modality conditions. Regression analyses found that characteristic connectivity metrics of the reading network showed a presentation modality dependent relationship with reading difficulty: Children with more segregated reading networks and those that used fewer of the available connections were those with the least severe reading difficulty. These results are consistent with the hypothesis that a lack of coordinated processing between the neural regions involved in phonological and orthographic processing contributes towards reading difficulty. |
| first_indexed | 2024-12-20T18:40:20Z |
| format | Article |
| id | doaj.art-e3361d0a7c8d45a9b09bd46d37adca18 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T18:40:20Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-e3361d0a7c8d45a9b09bd46d37adca182022-12-21T19:29:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-011312e020892310.1371/journal.pone.0208923Dyslexia on a continuum: A complex network approach.Erica S EdwardsKali BurkeJames R BoothChris McNorganWe investigated the efficacy of graph-theoretic metrics of task-related functional brain connectivity in predicting reading difficulty and explored the hypothesis that task conditions emphasizing audiovisual integration would be especially diagnostic of reading difficulty. An fMRI study was conducted in which 24 children (8 to 14 years old) who were previously diagnosed with dyslexia completed a rhyming judgment task under three presentation modality conditions. Regression analyses found that characteristic connectivity metrics of the reading network showed a presentation modality dependent relationship with reading difficulty: Children with more segregated reading networks and those that used fewer of the available connections were those with the least severe reading difficulty. These results are consistent with the hypothesis that a lack of coordinated processing between the neural regions involved in phonological and orthographic processing contributes towards reading difficulty.https://doi.org/10.1371/journal.pone.0208923 |
| spellingShingle | Erica S Edwards Kali Burke James R Booth Chris McNorgan Dyslexia on a continuum: A complex network approach. PLoS ONE |
| title | Dyslexia on a continuum: A complex network approach. |
| title_full | Dyslexia on a continuum: A complex network approach. |
| title_fullStr | Dyslexia on a continuum: A complex network approach. |
| title_full_unstemmed | Dyslexia on a continuum: A complex network approach. |
| title_short | Dyslexia on a continuum: A complex network approach. |
| title_sort | dyslexia on a continuum a complex network approach |
| url | https://doi.org/10.1371/journal.pone.0208923 |
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