Population Pharmacokinetics of Rituximab in Pediatric Patients With Frequent-Relapsing or Steroid-Dependent Nephrotic Syndrome

Population Pharmacokinetics of Rituximab in Pediatric Patients With Frequent-Relapsing or Steroid-Dependent Nephrotic Syndrome

Objectives: Rituximab is frequently used off-label for the treatment of frequent-relapsing nephrotic syndrome (FRNS) or steroid-dependent nephrotic syndrome (SDNS), but the relapse rate remained high and the dosing regimen varied widely. The objective of this study was to characterize rituximab phar...

Full description

Bibliographic Details
Main Authors: Yewei Chen, Qian Shen, Min Dong, Ye Xiong, Hong Xu, Zhiping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
rituximab
pharmacokinetics
children
nephrotic syndrome
dosing
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.725665/full

Similar Items

Similar Items