Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients

This retrospective study investigates differences in peri-/postoperative complications/outcomes of head and neck microvascular free flap reconstructions between female (FFP) and male flap patients (MFP).Evaluated variables: biological sex, age, ASA status, tumor type, preoperative radiation/chemothe...

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Main Authors: Nils H. Rohleder, Sina Heimüller, Klaus D. Wolff, Marco R. Kesting
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Advances in Oral and Maxillofacial Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667147622000577
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author Nils H. Rohleder
Sina Heimüller
Klaus D. Wolff
Marco R. Kesting
author_facet Nils H. Rohleder
Sina Heimüller
Klaus D. Wolff
Marco R. Kesting
author_sort Nils H. Rohleder
collection DOAJ
description This retrospective study investigates differences in peri-/postoperative complications/outcomes of head and neck microvascular free flap reconstructions between female (FFP) and male flap patients (MFP).Evaluated variables: biological sex, age, ASA status, tumor type, preoperative radiation/chemotherapy, medical comorbidities; flap type, reconstruction (primary/secondary), operative time; length of stay on ICU, prolonged stay on ICU and its reasons, length of hospitalization, prolonged hospitalization and its reasons; flap success, revisions, overall complications, mortality.N = 215 patients (86 FFP; 129 MFP) were included. MFP exhibited higher nicotine abuse (P < .001), received more large-volume flaps (P < .001), and operative time was longer (P = .013). Sex had no influence on postoperative and outcome variables.Biological sex has no influence on the postoperative course following head and neck microsurgical free flap reconstructions.
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spelling doaj.art-e33696446d434af6bf3fbead268f58eb2022-12-22T02:07:01ZengElsevierAdvances in Oral and Maxillofacial Surgery2667-14762022-07-017100307Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patientsNils H. Rohleder0Sina Heimüller1Klaus D. Wolff2Marco R. Kesting3Technical University of Munich, School of Medicine, Department of Oral and Maxillofacial Surgery, Ismaninger Str. 22, 81675, Munich, Germany; Corresponding author.Technical University of Munich, School of Medicine, Department of Oral and Maxillofacial Surgery, Ismaninger Str. 22, 81675, Munich, GermanyTechnical University of Munich, School of Medicine, Department of Oral and Maxillofacial Surgery, Ismaninger Str. 22, 81675, Munich, GermanyUniversity of Erlangen-Nuremberg, Department of Oral and Maxillofacial Surgery, Glückstr. 11, 91054, Erlangen, GermanyThis retrospective study investigates differences in peri-/postoperative complications/outcomes of head and neck microvascular free flap reconstructions between female (FFP) and male flap patients (MFP).Evaluated variables: biological sex, age, ASA status, tumor type, preoperative radiation/chemotherapy, medical comorbidities; flap type, reconstruction (primary/secondary), operative time; length of stay on ICU, prolonged stay on ICU and its reasons, length of hospitalization, prolonged hospitalization and its reasons; flap success, revisions, overall complications, mortality.N = 215 patients (86 FFP; 129 MFP) were included. MFP exhibited higher nicotine abuse (P < .001), received more large-volume flaps (P < .001), and operative time was longer (P = .013). Sex had no influence on postoperative and outcome variables.Biological sex has no influence on the postoperative course following head and neck microsurgical free flap reconstructions.http://www.sciencedirect.com/science/article/pii/S2667147622000577MicrosurgeryFree flapBiological sexHead and neckOutcomeDifference
spellingShingle Nils H. Rohleder
Sina Heimüller
Klaus D. Wolff
Marco R. Kesting
Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
Advances in Oral and Maxillofacial Surgery
Microsurgery
Free flap
Biological sex
Head and neck
Outcome
Difference
title Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
title_full Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
title_fullStr Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
title_full_unstemmed Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
title_short Influence of biological sex on intra- and postoperative course of microvascular free flap reconstructive surgery in the head and neck region: A retrospective analysis involving 215 patients
title_sort influence of biological sex on intra and postoperative course of microvascular free flap reconstructive surgery in the head and neck region a retrospective analysis involving 215 patients
topic Microsurgery
Free flap
Biological sex
Head and neck
Outcome
Difference
url http://www.sciencedirect.com/science/article/pii/S2667147622000577
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