Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens
Direct-fed microbials (DFMs) are live microorganisms which confer a health benefit to the host. The mode of action of DFMs involves multiple mechanisms, including direct inhibition of enteric pathogens and indirectly through competitive exclusion of pathogens by the normal gut microbiota. Addition...
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Format: | Article |
Language: | English |
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Japan Poultry Science Association
2010-04-01
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Series: | The Journal of Poultry Science |
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Online Access: | https://www.jstage.jst.go.jp/article/jpsa/47/2/47_009096/_pdf/-char/en |
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author | Kyungwoo Lee Hyun S. Lillehoj Gregory R. Siragusa |
author_facet | Kyungwoo Lee Hyun S. Lillehoj Gregory R. Siragusa |
author_sort | Kyungwoo Lee |
collection | DOAJ |
description | Direct-fed microbials (DFMs) are live microorganisms which confer a health benefit to the host. The mode of action of DFMs involves multiple mechanisms, including direct inhibition of enteric pathogens and indirectly through competitive exclusion of pathogens by the normal gut microbiota. Additionally, recent basic research efforts have focused on the effects of DFMs on promoting host immunity and on the complex interactions between the gut microflora and immune system development. This review will summarize the latest developments in DFM studies with particular emphasis on the underlying mechanisms of immune enhancement. |
first_indexed | 2024-03-13T08:34:24Z |
format | Article |
id | doaj.art-e33818921d39450485079b558768a05d |
institution | Directory Open Access Journal |
issn | 1346-7395 1349-0486 |
language | English |
last_indexed | 2024-03-13T08:34:24Z |
publishDate | 2010-04-01 |
publisher | Japan Poultry Science Association |
record_format | Article |
series | The Journal of Poultry Science |
spelling | doaj.art-e33818921d39450485079b558768a05d2023-05-31T00:53:25ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862010-04-0147210611410.2141/jpsa.009096jpsaDirect-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of ChickensKyungwoo Lee0Hyun S. Lillehoj1Gregory R. Siragusa2Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, USDA, USAAnimal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, USDA, USADanisco, Waukesha, USADirect-fed microbials (DFMs) are live microorganisms which confer a health benefit to the host. The mode of action of DFMs involves multiple mechanisms, including direct inhibition of enteric pathogens and indirectly through competitive exclusion of pathogens by the normal gut microbiota. Additionally, recent basic research efforts have focused on the effects of DFMs on promoting host immunity and on the complex interactions between the gut microflora and immune system development. This review will summarize the latest developments in DFM studies with particular emphasis on the underlying mechanisms of immune enhancement.https://www.jstage.jst.go.jp/article/jpsa/47/2/47_009096/_pdf/-char/enbacillus subtilisdirect-fed microbialsgut microfloraimmunomodulationpoultry |
spellingShingle | Kyungwoo Lee Hyun S. Lillehoj Gregory R. Siragusa Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens The Journal of Poultry Science bacillus subtilis direct-fed microbials gut microflora immunomodulation poultry |
title | Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens |
title_full | Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens |
title_fullStr | Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens |
title_full_unstemmed | Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens |
title_short | Direct-Fed Microbials and Their Impact on the Intestinal Microflora and Immune System of Chickens |
title_sort | direct fed microbials and their impact on the intestinal microflora and immune system of chickens |
topic | bacillus subtilis direct-fed microbials gut microflora immunomodulation poultry |
url | https://www.jstage.jst.go.jp/article/jpsa/47/2/47_009096/_pdf/-char/en |
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