Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases
Wells' syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2015-06-01
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| Series: | Case Reports in Dermatology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/432392 |
| _version_ | 1811233992785002496 |
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| author | Maxence Cormerais Florence Poizeau Laure Darrieux Laurent Tisseau Gilles Safa |
| author_facet | Maxence Cormerais Florence Poizeau Laure Darrieux Laurent Tisseau Gilles Safa |
| author_sort | Maxence Cormerais |
| collection | DOAJ |
| description | Wells' syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here, we report two cases of WS that masqueraded as bacterial facial cellulitis. Under treatment with oral prednisone and/or a combination therapy with levocetirizine and hydroxyzine, both patients showed a dramatic improvement of the skin lesions. These cases highlight the need for clinicians to consider WS in the differential diagnosis when evaluating a patient with facial cellulitis that does not respond to an initial antimicrobial regimen. In addition, our cases suggest that combination therapy with levocetirizine and hydroxyzine may be successfully used as corticosteroid-sparing treatment or to prevent relapse after the discontinuation of corticosteroid treatment. |
| first_indexed | 2024-04-12T11:29:19Z |
| format | Article |
| id | doaj.art-e338a4e8f0304fd9804350f41d20a2d6 |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-04-12T11:29:19Z |
| publishDate | 2015-06-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-e338a4e8f0304fd9804350f41d20a2d62022-12-22T03:35:08ZengKarger PublishersCase Reports in Dermatology1662-65672015-06-017211712210.1159/000432392432392Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two CasesMaxence CormeraisFlorence PoizeauLaure DarrieuxLaurent TisseauGilles SafaWells' syndrome (WS), or eosinophilic cellulitis, is an uncommon inflammatory dermatosis of unknown etiology that typically presents with pruritic cellulitis-like plaques on the extremities. Therefore, WS is often misdiagnosed as bacterial cellulitis due to its similarity in presentation. Here, we report two cases of WS that masqueraded as bacterial facial cellulitis. Under treatment with oral prednisone and/or a combination therapy with levocetirizine and hydroxyzine, both patients showed a dramatic improvement of the skin lesions. These cases highlight the need for clinicians to consider WS in the differential diagnosis when evaluating a patient with facial cellulitis that does not respond to an initial antimicrobial regimen. In addition, our cases suggest that combination therapy with levocetirizine and hydroxyzine may be successfully used as corticosteroid-sparing treatment or to prevent relapse after the discontinuation of corticosteroid treatment.http://www.karger.com/Article/FullText/432392Wellsߣ syndromeEosinophilic cellulitisFacial cellulitis |
| spellingShingle | Maxence Cormerais Florence Poizeau Laure Darrieux Laurent Tisseau Gilles Safa Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases Case Reports in Dermatology Wellsߣ syndrome Eosinophilic cellulitis Facial cellulitis |
| title | Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
| title_full | Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
| title_fullStr | Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
| title_full_unstemmed | Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
| title_short | Wells' Syndrome Mimicking Facial Cellulitis: A Report of Two Cases |
| title_sort | wells syndrome mimicking facial cellulitis a report of two cases |
| topic | Wellsߣ syndrome Eosinophilic cellulitis Facial cellulitis |
| url | http://www.karger.com/Article/FullText/432392 |
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