Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?

Abstract Background To study if pain relief after injection and arthroplasty correlate. Methods A retrospective cohort study included consecutive patients (n = 88; median age 64 (interquartile range (IQR) 22) years, 49 (56%) females) that received fluoroscopic-guided intra-articular hip injection wi...

Full description

Bibliographic Details
Main Authors: Thorsten Jentzsch, Yann K. Meyer, Ines Unterfrauner, Andrea B. Rosskopf, Christian W. Pfirrmann, Patrick O. Zingg
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-022-05969-4
_version_ 1797952733883400192
author Thorsten Jentzsch
Yann K. Meyer
Ines Unterfrauner
Andrea B. Rosskopf
Christian W. Pfirrmann
Patrick O. Zingg
author_facet Thorsten Jentzsch
Yann K. Meyer
Ines Unterfrauner
Andrea B. Rosskopf
Christian W. Pfirrmann
Patrick O. Zingg
author_sort Thorsten Jentzsch
collection DOAJ
description Abstract Background To study if pain relief after injection and arthroplasty correlate. Methods A retrospective cohort study included consecutive patients (n = 88; median age 64 (interquartile range (IQR) 22) years, 49 (56%) females) that received fluoroscopic-guided intra-articular hip injection with contrast agent, anaesthetic (diagnostic), and corticosteroid (therapeutic) before implantation of primary total hip arthroplasty. Pain scores were assessed pre-injection, post-injection after 15 min (diagnostic phase) at first clinical follow up (therapeutic phase; median 2 (IQR 2) months), and postoperatively (last follow up (median 15 (IQR 5) months)). Responders had reduction in pain score ≥ 20 (numeric rating scale 0–100) points. The primary outcome was the same (or inverse) response to injection and arthroplasty. Results The median pain scores were higher pre-injection (68 (IQR 30) points) compared to the diagnostic phase (18 (IQR 40) points; p < 0.001), therapeutic phase (50 (IQR 40) points; p < 0.001), and post-operatively (2 (IQR 15) points; p < 0.001). On the one hand, 69 (78%) cases had the same response in the diagnostic phase and post-operatively (rho = 0.58; p < 0.001; sensitivity 83%); on the other hand 32 (36%) cases had the same response in the therapeutic phase and post-operatively (rho = 0.25; p < 0.001; sensitivity 33%). Furthermore, 57% and 91% of patients had an even better response post-operatively than in the diagnostic and therapeutic phases. Conclusions Pre-operative intraarticular injection can predict pain relief after primary total hip arthroplasty. A positive response to hip arthroplasty may be better predicted by the response to local anaesthetic (diagnostic phase) than corticosteroids. Most patients (91%) with osteoarthritis may expect better pain relief after arthroplasty compared to the therapeutic phase after injection.
first_indexed 2024-04-10T22:50:55Z
format Article
id doaj.art-e3399e9558634bb0babafae9e135ed1a
institution Directory Open Access Journal
issn 1471-2474
language English
last_indexed 2024-04-10T22:50:55Z
publishDate 2023-01-01
publisher BMC
record_format Article
series BMC Musculoskeletal Disorders
spelling doaj.art-e3399e9558634bb0babafae9e135ed1a2023-01-15T12:02:14ZengBMCBMC Musculoskeletal Disorders1471-24742023-01-012411610.1186/s12891-022-05969-4Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?Thorsten Jentzsch0Yann K. Meyer1Ines Unterfrauner2Andrea B. Rosskopf3Christian W. Pfirrmann4Patrick O. Zingg5Department of Orthopaedics, Balgrist University Hospital, University of ZurichFaculty of Medicine, University of ZurichDepartment of Orthopaedics, Balgrist University Hospital, University of ZurichDepartment of Radiology, Balgrist University HospitalDepartment of Radiology, Balgrist University HospitalDepartment of Orthopaedics, Balgrist University Hospital, University of ZurichAbstract Background To study if pain relief after injection and arthroplasty correlate. Methods A retrospective cohort study included consecutive patients (n = 88; median age 64 (interquartile range (IQR) 22) years, 49 (56%) females) that received fluoroscopic-guided intra-articular hip injection with contrast agent, anaesthetic (diagnostic), and corticosteroid (therapeutic) before implantation of primary total hip arthroplasty. Pain scores were assessed pre-injection, post-injection after 15 min (diagnostic phase) at first clinical follow up (therapeutic phase; median 2 (IQR 2) months), and postoperatively (last follow up (median 15 (IQR 5) months)). Responders had reduction in pain score ≥ 20 (numeric rating scale 0–100) points. The primary outcome was the same (or inverse) response to injection and arthroplasty. Results The median pain scores were higher pre-injection (68 (IQR 30) points) compared to the diagnostic phase (18 (IQR 40) points; p < 0.001), therapeutic phase (50 (IQR 40) points; p < 0.001), and post-operatively (2 (IQR 15) points; p < 0.001). On the one hand, 69 (78%) cases had the same response in the diagnostic phase and post-operatively (rho = 0.58; p < 0.001; sensitivity 83%); on the other hand 32 (36%) cases had the same response in the therapeutic phase and post-operatively (rho = 0.25; p < 0.001; sensitivity 33%). Furthermore, 57% and 91% of patients had an even better response post-operatively than in the diagnostic and therapeutic phases. Conclusions Pre-operative intraarticular injection can predict pain relief after primary total hip arthroplasty. A positive response to hip arthroplasty may be better predicted by the response to local anaesthetic (diagnostic phase) than corticosteroids. Most patients (91%) with osteoarthritis may expect better pain relief after arthroplasty compared to the therapeutic phase after injection.https://doi.org/10.1186/s12891-022-05969-4PainInjectionSteroidsAnestheticsLocalHip
spellingShingle Thorsten Jentzsch
Yann K. Meyer
Ines Unterfrauner
Andrea B. Rosskopf
Christian W. Pfirrmann
Patrick O. Zingg
Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
BMC Musculoskeletal Disorders
Pain
Injection
Steroids
Anesthetics
Local
Hip
title Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
title_full Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
title_fullStr Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
title_full_unstemmed Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
title_short Can pre-operative intraarticular injection predict pain relief after total hip arthroplasty?
title_sort can pre operative intraarticular injection predict pain relief after total hip arthroplasty
topic Pain
Injection
Steroids
Anesthetics
Local
Hip
url https://doi.org/10.1186/s12891-022-05969-4
work_keys_str_mv AT thorstenjentzsch canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty
AT yannkmeyer canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty
AT inesunterfrauner canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty
AT andreabrosskopf canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty
AT christianwpfirrmann canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty
AT patrickozingg canpreoperativeintraarticularinjectionpredictpainreliefaftertotalhiparthroplasty