Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure

Purpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and low...

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Main Authors: Risa Minamidate, Tetsuya Toyono, Yuichi Asahina, Sho Yamazawa, Takashi Miyai
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993623000270
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author Risa Minamidate
Tetsuya Toyono
Yuichi Asahina
Sho Yamazawa
Takashi Miyai
author_facet Risa Minamidate
Tetsuya Toyono
Yuichi Asahina
Sho Yamazawa
Takashi Miyai
author_sort Risa Minamidate
collection DOAJ
description Purpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and lower eyelid margins of her right eye became adherent, and the eyelid remained closed for several years due to refusal of steroid treatment and aggravation of blepharitis. During the initial examination, a lesion with elevated white opacity on the corneal surface was observed. Subsequently, superficial keratectomy was performed. The histopathological findings were indicative of corneal keloid. Conclusions and Importance: Persistent atopic ocular surface inflammation and prolonged eyelid closure resulted in the formation of a corneal keloid.
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spelling doaj.art-e3413d41ce834171b8ed5ef8bb5326262023-05-19T04:46:08ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362023-06-0130101819Corneal keloid caused by persistent atopic eye disease and chronic eyelid closureRisa Minamidate0Tetsuya Toyono1Yuichi Asahina2Sho Yamazawa3Takashi Miyai4Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Department of Ophthalmology, Kanto Rosai Hospital, Kanagawa, JapanDepartment of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Corresponding author. Department of Ophthalmology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Department of Pathology, The University of Tokyo Hospital, Tokyo, JapanDepartment of Pathology, The University of Tokyo Hospital, Tokyo, JapanDepartment of Ophthalmology, The University of Tokyo Hospital, Tokyo, JapanPurpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and lower eyelid margins of her right eye became adherent, and the eyelid remained closed for several years due to refusal of steroid treatment and aggravation of blepharitis. During the initial examination, a lesion with elevated white opacity on the corneal surface was observed. Subsequently, superficial keratectomy was performed. The histopathological findings were indicative of corneal keloid. Conclusions and Importance: Persistent atopic ocular surface inflammation and prolonged eyelid closure resulted in the formation of a corneal keloid.http://www.sciencedirect.com/science/article/pii/S2451993623000270Corneal keloidAtopic blepharitisCorneal fibrosisKeratectomy
spellingShingle Risa Minamidate
Tetsuya Toyono
Yuichi Asahina
Sho Yamazawa
Takashi Miyai
Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
American Journal of Ophthalmology Case Reports
Corneal keloid
Atopic blepharitis
Corneal fibrosis
Keratectomy
title Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
title_full Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
title_fullStr Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
title_full_unstemmed Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
title_short Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
title_sort corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
topic Corneal keloid
Atopic blepharitis
Corneal fibrosis
Keratectomy
url http://www.sciencedirect.com/science/article/pii/S2451993623000270
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AT yuichiasahina cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure
AT shoyamazawa cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure
AT takashimiyai cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure