Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure
Purpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and low...
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Format: | Article |
Language: | English |
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Elsevier
2023-06-01
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Series: | American Journal of Ophthalmology Case Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993623000270 |
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author | Risa Minamidate Tetsuya Toyono Yuichi Asahina Sho Yamazawa Takashi Miyai |
author_facet | Risa Minamidate Tetsuya Toyono Yuichi Asahina Sho Yamazawa Takashi Miyai |
author_sort | Risa Minamidate |
collection | DOAJ |
description | Purpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and lower eyelid margins of her right eye became adherent, and the eyelid remained closed for several years due to refusal of steroid treatment and aggravation of blepharitis. During the initial examination, a lesion with elevated white opacity on the corneal surface was observed. Subsequently, superficial keratectomy was performed. The histopathological findings were indicative of corneal keloid. Conclusions and Importance: Persistent atopic ocular surface inflammation and prolonged eyelid closure resulted in the formation of a corneal keloid. |
first_indexed | 2024-03-13T10:28:22Z |
format | Article |
id | doaj.art-e3413d41ce834171b8ed5ef8bb532626 |
institution | Directory Open Access Journal |
issn | 2451-9936 |
language | English |
last_indexed | 2024-03-13T10:28:22Z |
publishDate | 2023-06-01 |
publisher | Elsevier |
record_format | Article |
series | American Journal of Ophthalmology Case Reports |
spelling | doaj.art-e3413d41ce834171b8ed5ef8bb5326262023-05-19T04:46:08ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362023-06-0130101819Corneal keloid caused by persistent atopic eye disease and chronic eyelid closureRisa Minamidate0Tetsuya Toyono1Yuichi Asahina2Sho Yamazawa3Takashi Miyai4Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Department of Ophthalmology, Kanto Rosai Hospital, Kanagawa, JapanDepartment of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Corresponding author. Department of Ophthalmology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan; Department of Pathology, The University of Tokyo Hospital, Tokyo, JapanDepartment of Pathology, The University of Tokyo Hospital, Tokyo, JapanDepartment of Ophthalmology, The University of Tokyo Hospital, Tokyo, JapanPurpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment. Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and lower eyelid margins of her right eye became adherent, and the eyelid remained closed for several years due to refusal of steroid treatment and aggravation of blepharitis. During the initial examination, a lesion with elevated white opacity on the corneal surface was observed. Subsequently, superficial keratectomy was performed. The histopathological findings were indicative of corneal keloid. Conclusions and Importance: Persistent atopic ocular surface inflammation and prolonged eyelid closure resulted in the formation of a corneal keloid.http://www.sciencedirect.com/science/article/pii/S2451993623000270Corneal keloidAtopic blepharitisCorneal fibrosisKeratectomy |
spellingShingle | Risa Minamidate Tetsuya Toyono Yuichi Asahina Sho Yamazawa Takashi Miyai Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure American Journal of Ophthalmology Case Reports Corneal keloid Atopic blepharitis Corneal fibrosis Keratectomy |
title | Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
title_full | Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
title_fullStr | Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
title_full_unstemmed | Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
title_short | Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
title_sort | corneal keloid caused by persistent atopic eye disease and chronic eyelid closure |
topic | Corneal keloid Atopic blepharitis Corneal fibrosis Keratectomy |
url | http://www.sciencedirect.com/science/article/pii/S2451993623000270 |
work_keys_str_mv | AT risaminamidate cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure AT tetsuyatoyono cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure AT yuichiasahina cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure AT shoyamazawa cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure AT takashimiyai cornealkeloidcausedbypersistentatopiceyediseaseandchroniceyelidclosure |