The Diverse Function of PD-1/PD-L Pathway Beyond Cancer

The recent success of PD-1 and PD-L1 blockade in cancer therapy illustrates the important role of the PD-1/PD-L1 pathway in the regulation of antitumor immune responses. However, signaling regulated by the PD-1/PD-L pathway is also associated with substantial inflammatory effects that can resemble t...

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Bibliographic Details
Main Authors: Weiting Qin, Lipeng Hu, Xueli Zhang, Shuheng Jiang, Jun Li, Zhigang Zhang, Xu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02298/full