Argonaute 4 as an Effector Protein in RNA-Directed DNA Methylation in Human Cells

Argonaute 4 as an Effector Protein in RNA-Directed DNA Methylation in Human Cells

DNA methylation of specific genome locations contributes to the distinct functions of multicellular organisms. DNA methylation can be governed by RNA-dependent DNA methylation (RdDM). RdDM is carried out by endogenous small-RNA-guided epigenomic editing complexes that add a methyl group to a precise...

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Bibliographic Details
Main Authors: Kanwalat Chalertpet, Piyapat Pin-on, Chatchawit Aporntewan, Maturada Patchsung, Praewphan Ingrungruanglert, Nipan Israsena, Apiwat Mutirangura
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Genetics
Subjects:
human Argonaute 4
human RNA-directed DNA methylation
human RdDM
CPP-AGO4
epigenomic editing
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00645/full

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