P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.

P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.

The O-acetylation of polysaccharides is a common modification used by pathogenic organisms to protect against external forces. Pseudomonas aeruginosa secretes the anionic, O-acetylated exopolysaccharide alginate during chronic infection in the lungs of cystic fibrosis patients to form the major cons...

Full description

Bibliographic Details
Main Authors: Perrin Baker, Tyler Ricer, Patrick J Moynihan, Elena N Kitova, Marthe T C Walvoort, Dustin J Little, John C Whitney, Karen Dawson, Joel T Weadge, Howard Robinson, Dennis E Ohman, Jeroen D C Codée, John S Klassen, Anthony J Clarke, P Lynne Howell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4148444?pdf=render

Similar Items

Similar Items