Fabrication of paper-based microfluidic device using printed circuit technology
This paper describes the use of a printed circuit technology to generate hydrophilic channels in a filter paper. Patterns of channels were designed using Protel soft, and printed on a blank paper. Then, the patterns were transferred to a sheet copper using a thermal transfer printer. The sheet coppe...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2012-06-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/1.4733346 |
| _version_ | 1811229329312448512 |
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| author | An-liang Zhang Yan Zha |
| author_facet | An-liang Zhang Yan Zha |
| author_sort | An-liang Zhang |
| collection | DOAJ |
| description | This paper describes the use of a printed circuit technology to generate hydrophilic channels in a filter paper. Patterns of channels were designed using Protel soft, and printed on a blank paper. Then, the patterns were transferred to a sheet copper using a thermal transfer printer. The sheet copper with patterns was dipped into ferric chloride solution to etch the whole patterns of the sheet copper. At last, the etched sheet copper was coated with a film of paraffin and then a filter paper. An electric iron was used to heat the other side of the sheet copper. The melting paraffin penetrated full thickness of the filter paper and formed a hydrophobic “wall”. Colorimetric assays for the presence of protein and glucose were demonstrated using the paper-based device. The work is helpful to researchers to fabricate paper-based microfluidic devices for monitoring health and detecting disease. |
| first_indexed | 2024-04-12T10:12:49Z |
| format | Article |
| id | doaj.art-e351bd860b8e4eccbafc35d8b07b758c |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-04-12T10:12:49Z |
| publishDate | 2012-06-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-e351bd860b8e4eccbafc35d8b07b758c2022-12-22T03:37:16ZengAIP Publishing LLCAIP Advances2158-32262012-06-0122022171022171-610.1063/1.4733346071202ADVFabrication of paper-based microfluidic device using printed circuit technologyAn-liang Zhang0Yan Zha1Department of electronic Engineering, Ningbo University, Ningbo, 315211, P.R.ChinaDepartment of electronic Engineering, Ningbo University, Ningbo, 315211, P.R.ChinaThis paper describes the use of a printed circuit technology to generate hydrophilic channels in a filter paper. Patterns of channels were designed using Protel soft, and printed on a blank paper. Then, the patterns were transferred to a sheet copper using a thermal transfer printer. The sheet copper with patterns was dipped into ferric chloride solution to etch the whole patterns of the sheet copper. At last, the etched sheet copper was coated with a film of paraffin and then a filter paper. An electric iron was used to heat the other side of the sheet copper. The melting paraffin penetrated full thickness of the filter paper and formed a hydrophobic “wall”. Colorimetric assays for the presence of protein and glucose were demonstrated using the paper-based device. The work is helpful to researchers to fabricate paper-based microfluidic devices for monitoring health and detecting disease.http://dx.doi.org/10.1063/1.4733346 |
| spellingShingle | An-liang Zhang Yan Zha Fabrication of paper-based microfluidic device using printed circuit technology AIP Advances |
| title | Fabrication of paper-based microfluidic device using printed circuit technology |
| title_full | Fabrication of paper-based microfluidic device using printed circuit technology |
| title_fullStr | Fabrication of paper-based microfluidic device using printed circuit technology |
| title_full_unstemmed | Fabrication of paper-based microfluidic device using printed circuit technology |
| title_short | Fabrication of paper-based microfluidic device using printed circuit technology |
| title_sort | fabrication of paper based microfluidic device using printed circuit technology |
| url | http://dx.doi.org/10.1063/1.4733346 |
| work_keys_str_mv | AT anliangzhang fabricationofpaperbasedmicrofluidicdeviceusingprintedcircuittechnology AT yanzha fabricationofpaperbasedmicrofluidicdeviceusingprintedcircuittechnology |