Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites

Electrolyte imbalance causes suppression of NK and T cell effector function in malignant ascites

Abstract Background Malignant ascites commonly occurs in advanced or recurrent stages of epithelial ovarian cancer during peritoneal carcinomatosis and is correlated with poor prognosis. Due to its complex composition of cellular and acellular components malignant ascites creates a unique tumor micr...

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Bibliographic Details
Main Authors: Antonio Hrvat, Mathias Schmidt, Bernd Wagner, Denise Zwanziger, Rainer Kimmig, Lothar Volbracht, Sven Brandau, Nina Mallmann-Gottschalk
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
NK cell
Ascites
Immunosuppression
Sodium
Ovarian cancer
T cell
Online Access:https://doi.org/10.1186/s13046-023-02798-8

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