Advances in patient-controlled analgesia: the role of fentanyl ITS

Ian Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient’s peri-operative care package. Good analgesia has been shown to reduce...

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Main Authors: Ian Power, Jon G McCormack
Format: Article
Language:English
Published: Dove Medical Press 2009-01-01
Series:Medical Devices: Evidence and Research
Online Access:http://www.dovepress.com/advances-in-patient-controlled-analgesia-the-role-of-fentanyl-its-a2785
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author Ian Power
Jon G McCormack
author_facet Ian Power
Jon G McCormack
author_sort Ian Power
collection DOAJ
description Ian Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient’s peri-operative care package. Good analgesia has been shown to reduce the incidence of cardiovascular, respiratory and thrombo-embolic complications following surgery. Satisfactory analgesia facilitates early patient ambulation following surgery, which may reduce in-patient stay. Patient-controlled analgesia (PCA) systems are a well established standard therapy for acute post-operative pain; however some practical limitations limit their clinical utility. The fentanyl inotophoretic transdermal system (ITS) is a novel self-contained needle-free PCA device, which delivers boluses of fentanyl transdermally. This system has been shown to provide analgesia equivalent to conventional PCA modalities, with unique design features that may confer advantages to patients and staff, including facilitating patient mobilization in the post-operative phase. This review will discuss the technology of iontophoretic systems, the pharmacology of transdermal fentanyl delivery, and some practical implications of the fentanyl ITS.Keywords: iontophoresis, transdermal, patient-controlled analgesia, fentanyl, post-operative pain
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spelling doaj.art-e3559456fc674900989ee34aa3ba387f2022-12-21T20:12:12ZengDove Medical PressMedical Devices: Evidence and Research1179-14702009-01-012008default4957Advances in patient-controlled analgesia: the role of fentanyl ITSIan PowerJon G McCormackIan Power, Jon G McCormackDepartment of Anaesthesia, Critical Care and Pain Medicine, The University of Edinburgh, Royal Infirmary, Edinburgh, UKAbstract: Effective pain relief is an essential component of a patient’s peri-operative care package. Good analgesia has been shown to reduce the incidence of cardiovascular, respiratory and thrombo-embolic complications following surgery. Satisfactory analgesia facilitates early patient ambulation following surgery, which may reduce in-patient stay. Patient-controlled analgesia (PCA) systems are a well established standard therapy for acute post-operative pain; however some practical limitations limit their clinical utility. The fentanyl inotophoretic transdermal system (ITS) is a novel self-contained needle-free PCA device, which delivers boluses of fentanyl transdermally. This system has been shown to provide analgesia equivalent to conventional PCA modalities, with unique design features that may confer advantages to patients and staff, including facilitating patient mobilization in the post-operative phase. This review will discuss the technology of iontophoretic systems, the pharmacology of transdermal fentanyl delivery, and some practical implications of the fentanyl ITS.Keywords: iontophoresis, transdermal, patient-controlled analgesia, fentanyl, post-operative painhttp://www.dovepress.com/advances-in-patient-controlled-analgesia-the-role-of-fentanyl-its-a2785
spellingShingle Ian Power
Jon G McCormack
Advances in patient-controlled analgesia: the role of fentanyl ITS
Medical Devices: Evidence and Research
title Advances in patient-controlled analgesia: the role of fentanyl ITS
title_full Advances in patient-controlled analgesia: the role of fentanyl ITS
title_fullStr Advances in patient-controlled analgesia: the role of fentanyl ITS
title_full_unstemmed Advances in patient-controlled analgesia: the role of fentanyl ITS
title_short Advances in patient-controlled analgesia: the role of fentanyl ITS
title_sort advances in patient controlled analgesia the role of fentanyl its
url http://www.dovepress.com/advances-in-patient-controlled-analgesia-the-role-of-fentanyl-its-a2785
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