Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis
Introduction The current manuscript presents a protocol for a systematic review and meta-analysis of the evidence regarding the determinants of responsiveness to multidisciplinary management of chronic pain, with pain intensity, pain-related interference, physical functioning and health-related qual...
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Format: | Article |
Language: | English |
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BMJ Publishing Group
2022-09-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/12/9/e057481.full |
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author | Petteri Oura Markus Paananen Maiju Marttinen Merja Huttunen Pekka Vartiainen |
author_facet | Petteri Oura Markus Paananen Maiju Marttinen Merja Huttunen Pekka Vartiainen |
author_sort | Petteri Oura |
collection | DOAJ |
description | Introduction The current manuscript presents a protocol for a systematic review and meta-analysis of the evidence regarding the determinants of responsiveness to multidisciplinary management of chronic pain, with pain intensity, pain-related interference, physical functioning and health-related quality of life as the main outcomes, with consideration to multiple secondary outcomes.Methods and analysis To identify relevant studies, the Ovid MEDLINE, PubMed, Ovid PsycINFO, EBSCO CINAHL and Scopus databases will be searched for all studies exploring factors associated with responsiveness to multidisciplinary pain management from study inception to the present. Cohorts, case–control studies and randomised controlled trials will be included. Independent screening for eligible studies will be completed by a total of four researchers using defined criteria. Data extraction will be executed by two researchers. Study heterogeneity will be estimated using the I2 index. A meta-analysis will be performed using random effects models. Publication bias will be evaluated by means of funnel plots and Egger’s test.Ethics and dissemination The proposed study does not involve collection of primary data. Therefore, no ethical approval is required. The results of the systematic review and meta-analysis will be presented in a peer-reviewed journal and at conferences.PROSPERO registration number CRD42021236424. |
first_indexed | 2024-04-13T18:32:42Z |
format | Article |
id | doaj.art-e355ca9a1da14ab4b0844b1c97f772c6 |
institution | Directory Open Access Journal |
issn | 2044-6055 |
language | English |
last_indexed | 2024-04-13T18:32:42Z |
publishDate | 2022-09-01 |
publisher | BMJ Publishing Group |
record_format | Article |
series | BMJ Open |
spelling | doaj.art-e355ca9a1da14ab4b0844b1c97f772c62022-12-22T02:35:01ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2021-057481Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysisPetteri Oura0Markus Paananen1Maiju Marttinen2Merja Huttunen3Pekka Vartiainen4Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, FinlandCenter for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, FinlandThe Finnish Center for Pediatric and Adolescent Pain Management and Research, New Children’s Hospital, Helsinki University Hospital, Helsinki University Central Hospital, Helsinki, FinlandDepartment of Anesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital, Helsinki, FinlandDepartment of Paediatrics, Päijät-Häme Central Hospital, Lahti, FinlandIntroduction The current manuscript presents a protocol for a systematic review and meta-analysis of the evidence regarding the determinants of responsiveness to multidisciplinary management of chronic pain, with pain intensity, pain-related interference, physical functioning and health-related quality of life as the main outcomes, with consideration to multiple secondary outcomes.Methods and analysis To identify relevant studies, the Ovid MEDLINE, PubMed, Ovid PsycINFO, EBSCO CINAHL and Scopus databases will be searched for all studies exploring factors associated with responsiveness to multidisciplinary pain management from study inception to the present. Cohorts, case–control studies and randomised controlled trials will be included. Independent screening for eligible studies will be completed by a total of four researchers using defined criteria. Data extraction will be executed by two researchers. Study heterogeneity will be estimated using the I2 index. A meta-analysis will be performed using random effects models. Publication bias will be evaluated by means of funnel plots and Egger’s test.Ethics and dissemination The proposed study does not involve collection of primary data. Therefore, no ethical approval is required. The results of the systematic review and meta-analysis will be presented in a peer-reviewed journal and at conferences.PROSPERO registration number CRD42021236424.https://bmjopen.bmj.com/content/12/9/e057481.full |
spellingShingle | Petteri Oura Markus Paananen Maiju Marttinen Merja Huttunen Pekka Vartiainen Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis BMJ Open |
title | Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis |
title_full | Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis |
title_fullStr | Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis |
title_full_unstemmed | Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis |
title_short | Determinants of responsiveness to multidisciplinary chronic pain management interventions: protocol for a systematic review and meta-analysis |
title_sort | determinants of responsiveness to multidisciplinary chronic pain management interventions protocol for a systematic review and meta analysis |
url | https://bmjopen.bmj.com/content/12/9/e057481.full |
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