The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia
Objective: Iron deficiency anemia is the most common cause of microcytic anemia throughout the world. Ferritin levels are good indicators of iron stores; however, levels may increase irrespective of iron stores in cases of chronic disease. Therefore, it is difficult to diagnose iron deficiency anemi...
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| Format: | Article |
| Language: | English |
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Atatürk University
2011-04-01
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| Series: | Eurasian Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.eajm.org/text.php3?id=376 |
| _version_ | 1827163163449098240 |
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| author | Osman Yokus Bilal Yilmaz Murat Albayrak Ozlem Sahin Balcik Mehmet Rami Helvaci Engin Sennaroglu |
| author_facet | Osman Yokus Bilal Yilmaz Murat Albayrak Ozlem Sahin Balcik Mehmet Rami Helvaci Engin Sennaroglu |
| author_sort | Osman Yokus |
| collection | DOAJ |
| description | Objective: Iron deficiency anemia is the most common cause of microcytic anemia throughout the world. Ferritin levels are good indicators of iron stores; however, levels may increase irrespective of iron stores in cases of chronic disease. Therefore, it is difficult to diagnose iron deficiency anemia coexisting with anemia of chronic disease. Materials and Methods: To determine the level of transferrin receptor in subjects, 30 patients with iron deficiency anemia, 30 patients with anemia of chronic disease and 30 patients with both diseases were included in the study. Results: Mean serum transferrin receptor levels were 5.99±2.98 mg/L in the iron deficiency anemia group, 1.90±1.15 mg/L in the anemia of chronic disease group and 3.07±0.90 mg/L in the combination group. Comparing groups with each other revealed significant differences (p<0.05). Conclusion: It is concluded that the assessment of serum transferrin receptor levels is a useful method for the diagnosis of iron deficiency anemia in patients. |
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| format | Article |
| id | doaj.art-e35794deb7ff49c6b892304c9927d23d |
| institution | Directory Open Access Journal |
| issn | 1308-8734 1308-8742 |
| language | English |
| last_indexed | 2025-03-21T00:56:20Z |
| publishDate | 2011-04-01 |
| publisher | Atatürk University |
| record_format | Article |
| series | Eurasian Journal of Medicine |
| spelling | doaj.art-e35794deb7ff49c6b892304c9927d23d2024-08-03T04:50:03ZengAtatürk UniversityEurasian Journal of Medicine1308-87341308-87422011-04-014301912The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency AnemiaOsman YokusBilal YilmazMurat AlbayrakOzlem Sahin BalcikMehmet Rami HelvaciEngin SennarogluObjective: Iron deficiency anemia is the most common cause of microcytic anemia throughout the world. Ferritin levels are good indicators of iron stores; however, levels may increase irrespective of iron stores in cases of chronic disease. Therefore, it is difficult to diagnose iron deficiency anemia coexisting with anemia of chronic disease. Materials and Methods: To determine the level of transferrin receptor in subjects, 30 patients with iron deficiency anemia, 30 patients with anemia of chronic disease and 30 patients with both diseases were included in the study. Results: Mean serum transferrin receptor levels were 5.99±2.98 mg/L in the iron deficiency anemia group, 1.90±1.15 mg/L in the anemia of chronic disease group and 3.07±0.90 mg/L in the combination group. Comparing groups with each other revealed significant differences (p<0.05). Conclusion: It is concluded that the assessment of serum transferrin receptor levels is a useful method for the diagnosis of iron deficiency anemia in patients.http://www.eajm.org/text.php3?id=376Anemia of chronic diseaseIron deficiency anemiaSerum transferrin receptor level |
| spellingShingle | Osman Yokus Bilal Yilmaz Murat Albayrak Ozlem Sahin Balcik Mehmet Rami Helvaci Engin Sennaroglu The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia Eurasian Journal of Medicine Anemia of chronic disease Iron deficiency anemia Serum transferrin receptor level |
| title | The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia |
| title_full | The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia |
| title_fullStr | The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia |
| title_full_unstemmed | The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia |
| title_short | The Significance of Serum Transferrin Receptor Levels in the Diagnosis of the Coexistence of Anemia of Chronic Disease and Iron Deficiency Anemia |
| title_sort | significance of serum transferrin receptor levels in the diagnosis of the coexistence of anemia of chronic disease and iron deficiency anemia |
| topic | Anemia of chronic disease Iron deficiency anemia Serum transferrin receptor level |
| url | http://www.eajm.org/text.php3?id=376 |
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