Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies

Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies

Based on the success of tumor-infiltrating lymphocytes (TIL)-based therapies, personalized adoptive cell therapies (ACT) targeting neoantigens have the potential to become a disruptive technology and lead to highly effective treatments for cancer patients for whom no other options exist. ACT of TIL,...

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Bibliographic Details
Main Authors: Florian Kast, Christian Klein, Pablo Umaña, Alena Gros, Stephan Gasser
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
adoptive cell therapy
act
neoantigen
t cell
cancer
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1869389

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