Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction?
Objective: To determine the relationship between a Chlamydia trachomatis PCR positive diagnosis from cervical canal swabs and the presence of tubal diseases among infertile women in Vietnam. Methods: In this cross-sectional descriptive study, women who sought infertility treatment at the Center for...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2020-03-01
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| Series: | Fertility & Reproduction |
| Subjects: | |
| Online Access: | http://www.worldscientific.com/doi/epdf/10.1142/S2661318220500012 |
| _version_ | 1818452177074520064 |
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| author | Minh Tam Le Vu Quoc Huy Nguyen Le Na Thi Nguyen Viet Quynh Tram Ngo Hoang Bach Nguyen Ngoc Thanh Cao |
| author_facet | Minh Tam Le Vu Quoc Huy Nguyen Le Na Thi Nguyen Viet Quynh Tram Ngo Hoang Bach Nguyen Ngoc Thanh Cao |
| author_sort | Minh Tam Le |
| collection | DOAJ |
| description | Objective: To determine the relationship between a Chlamydia trachomatis PCR positive diagnosis from cervical canal swabs and the presence of tubal diseases among infertile women in Vietnam.
Methods: In this cross-sectional descriptive study, women who sought infertility treatment at the Center for Reproductive Endocrinology & Infertility, Hue University Hospital, Vietnam, from June 2016 to June 2017 were enrolled. All study participants were interviewed, and PCR tests were then performed to diagnose Chlamydia from cervical canal swabs. Hysterosalpingogram (HSG) was carried out to examine the uterine cavity and fallopian tubes.
Results: Among 568 women whose mean age was 32.0 ± 5.1 years, the prevalence of C. trachomatis infection as detected by PCR was 5.8%. Eighty-one percent (460/568) of infertile women had normal HSG results, and abnormal HSG results were more frequent in women over 35 years old, in women with secondary infertility, and in those with a history of miscarriage or genital tract infection. However, there was no relationship between C. trachomatis PCR positivity and HSG results in infertile women.
Conclusions: The diagnosis of C. trachomatis infection using the cervical swabs is the useful but not an effective method for routine practice for predicting tubal obstruction in infertile women. |
| first_indexed | 2024-12-14T21:18:56Z |
| format | Article |
| id | doaj.art-e35ff42e41b74679a1864571d6229d9c |
| institution | Directory Open Access Journal |
| issn | 2661-3182 2661-3174 |
| language | English |
| last_indexed | 2024-12-14T21:18:56Z |
| publishDate | 2020-03-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Fertility & Reproduction |
| spelling | doaj.art-e35ff42e41b74679a1864571d6229d9c2022-12-21T22:47:00ZengWorld Scientific PublishingFertility & Reproduction2661-31822661-31742020-03-01213810.1142/S266131822050001210.1142/S2661318220500012Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction?Minh Tam Le0Vu Quoc Huy Nguyen1Le Na Thi Nguyen2Viet Quynh Tram Ngo3Hoang Bach Nguyen4Ngoc Thanh Cao5Center for Reproductive Endocrinology and Infertility, Hue University Hospital, Hue University, VietnamDepartment of Obstetrics and Gynecology, Hue University of Medicine and Pharmacy, Hue University, VietnamDepartment of Obstetrics and Gynecology, Hue University of Medicine and Pharmacy, Hue University, VietnamDepartment of Microbiology, Hue University of Medicine and Pharmacy, Hue University, VietnamDepartment of Microbiology, Hue University of Medicine and Pharmacy, Hue University, VietnamCenter for Reproductive Endocrinology and Infertility, Hue University Hospital, Hue University, VietnamObjective: To determine the relationship between a Chlamydia trachomatis PCR positive diagnosis from cervical canal swabs and the presence of tubal diseases among infertile women in Vietnam. Methods: In this cross-sectional descriptive study, women who sought infertility treatment at the Center for Reproductive Endocrinology & Infertility, Hue University Hospital, Vietnam, from June 2016 to June 2017 were enrolled. All study participants were interviewed, and PCR tests were then performed to diagnose Chlamydia from cervical canal swabs. Hysterosalpingogram (HSG) was carried out to examine the uterine cavity and fallopian tubes. Results: Among 568 women whose mean age was 32.0 ± 5.1 years, the prevalence of C. trachomatis infection as detected by PCR was 5.8%. Eighty-one percent (460/568) of infertile women had normal HSG results, and abnormal HSG results were more frequent in women over 35 years old, in women with secondary infertility, and in those with a history of miscarriage or genital tract infection. However, there was no relationship between C. trachomatis PCR positivity and HSG results in infertile women. Conclusions: The diagnosis of C. trachomatis infection using the cervical swabs is the useful but not an effective method for routine practice for predicting tubal obstruction in infertile women.http://www.worldscientific.com/doi/epdf/10.1142/S2661318220500012chlamydia trachomatisinfertilitycervical swabtubal disorders |
| spellingShingle | Minh Tam Le Vu Quoc Huy Nguyen Le Na Thi Nguyen Viet Quynh Tram Ngo Hoang Bach Nguyen Ngoc Thanh Cao Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? Fertility & Reproduction chlamydia trachomatis infertility cervical swab tubal disorders |
| title | Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? |
| title_full | Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? |
| title_fullStr | Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? |
| title_full_unstemmed | Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? |
| title_short | Is Chlamydia trachomatis PCR Detection from Cervical Canal Swabs Associated with Tubal Obstruction? |
| title_sort | is chlamydia trachomatis pcr detection from cervical canal swabs associated with tubal obstruction |
| topic | chlamydia trachomatis infertility cervical swab tubal disorders |
| url | http://www.worldscientific.com/doi/epdf/10.1142/S2661318220500012 |
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