A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract

A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract

BackgroundChronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by chronic inflammation upon inhalation of noxious particles, e.g., cigarette smoke. FAM13A is one of the genes often found to be associated with COPD, however its function in the pathophysiology of CO...

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Bibliographic Details
Main Authors: Qing Chen, Maaike de Vries, Kingsley Okechukwu Nwozor, Jacobien A. Noordhoek, Corry-Anke Brandsma, H. Marike Boezen, Irene H. Heijink
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
COPD-Chronic obstructive pulmonary disease
FAM13A
airway epithelium
barrier function
CXCL8
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.690936/full

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