New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation

ABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learnin...

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Main Authors: Masami Takahashi, Makoto Itakura, Masakazu Kataoka
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326131
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author Masami Takahashi
Makoto Itakura
Masakazu Kataoka
author_facet Masami Takahashi
Makoto Itakura
Masakazu Kataoka
author_sort Masami Takahashi
collection DOAJ
description ABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learning and memory. Various protein kinases play important roles in the regulation, and candidates for protein substrates essential for the regulation have been identified.
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spelling doaj.art-e3714cc12d2f45e19f5047e17b7359be2022-12-22T00:49:17ZengElsevierJournal of Pharmacological Sciences1347-86132003-01-019314145New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by PhosphorylationMasami Takahashi0Makoto Itakura1Masakazu Kataoka2Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara-shi, Kanagawa 228-8555, Japan; CREST, JST (Japan Science and Technology)Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara-shi, Kanagawa 228-8555, JapanDepartment of Enviromental Science and Technology, Faculty of Engineering, Shinshu University, Wakasato 4-17-11, Nagano-shi, Nagano 380-8553, JapanABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learning and memory. Various protein kinases play important roles in the regulation, and candidates for protein substrates essential for the regulation have been identified.http://www.sciencedirect.com/science/article/pii/S1347861319326131
spellingShingle Masami Takahashi
Makoto Itakura
Masakazu Kataoka
New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
Journal of Pharmacological Sciences
title New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
title_full New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
title_fullStr New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
title_full_unstemmed New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
title_short New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
title_sort new aspects of neurotransmitter releasee and exocytosis regulation of neurotransmitter release by phosphorylation
url http://www.sciencedirect.com/science/article/pii/S1347861319326131
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AT makotoitakura newaspectsofneurotransmitterreleaseeandexocytosisregulationofneurotransmitterreleasebyphosphorylation
AT masakazukataoka newaspectsofneurotransmitterreleaseeandexocytosisregulationofneurotransmitterreleasebyphosphorylation