New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation
ABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learnin...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2003-01-01
|
Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319326131 |
_version_ | 1818540565849964544 |
---|---|
author | Masami Takahashi Makoto Itakura Masakazu Kataoka |
author_facet | Masami Takahashi Makoto Itakura Masakazu Kataoka |
author_sort | Masami Takahashi |
collection | DOAJ |
description | ABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learning and memory. Various protein kinases play important roles in the regulation, and candidates for protein substrates essential for the regulation have been identified. |
first_indexed | 2024-12-11T21:57:03Z |
format | Article |
id | doaj.art-e3714cc12d2f45e19f5047e17b7359be |
institution | Directory Open Access Journal |
issn | 1347-8613 |
language | English |
last_indexed | 2024-12-11T21:57:03Z |
publishDate | 2003-01-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Pharmacological Sciences |
spelling | doaj.art-e3714cc12d2f45e19f5047e17b7359be2022-12-22T00:49:17ZengElsevierJournal of Pharmacological Sciences1347-86132003-01-019314145New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by PhosphorylationMasami Takahashi0Makoto Itakura1Masakazu Kataoka2Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara-shi, Kanagawa 228-8555, Japan; CREST, JST (Japan Science and Technology)Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara-shi, Kanagawa 228-8555, JapanDepartment of Enviromental Science and Technology, Faculty of Engineering, Shinshu University, Wakasato 4-17-11, Nagano-shi, Nagano 380-8553, JapanABSTRACT: Synaptic transmission is conducted by neurotransmitters released from nerve terminals. Neurotransmitter release is regulated both positively and negatively by multiple mechanisms, and its regulation is believed to be one of the important mechanisms of synaptic plasticity underlying learning and memory. Various protein kinases play important roles in the regulation, and candidates for protein substrates essential for the regulation have been identified.http://www.sciencedirect.com/science/article/pii/S1347861319326131 |
spellingShingle | Masami Takahashi Makoto Itakura Masakazu Kataoka New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation Journal of Pharmacological Sciences |
title | New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation |
title_full | New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation |
title_fullStr | New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation |
title_full_unstemmed | New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation |
title_short | New Aspects of Neurotransmitter Releasee and Exocytosis: Regulation of Neurotransmitter Release by Phosphorylation |
title_sort | new aspects of neurotransmitter releasee and exocytosis regulation of neurotransmitter release by phosphorylation |
url | http://www.sciencedirect.com/science/article/pii/S1347861319326131 |
work_keys_str_mv | AT masamitakahashi newaspectsofneurotransmitterreleaseeandexocytosisregulationofneurotransmitterreleasebyphosphorylation AT makotoitakura newaspectsofneurotransmitterreleaseeandexocytosisregulationofneurotransmitterreleasebyphosphorylation AT masakazukataoka newaspectsofneurotransmitterreleaseeandexocytosisregulationofneurotransmitterreleasebyphosphorylation |